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Table 5 The univariate and multivariate regression including possible predictors of spontaneous HCV clearance

From: Paraoxonase 1 gene (PON1) variants concerning hepatitis C virus (HCV) spontaneous clearance in hemodialysis individuals: a case–control study

Parameter

Level of effect

Odds ratio

Odds ratio Upper 95.0% CL

Odds ratio Lower 95.0% CL

P-value

The univariate regression analysis

 Age at the RRT onset (years)

 

1.019

1.004

1.034

0.014

 RRT duration (years)

 

0.95

0.919

0.982

0.003

 PON1 rs854560 TT vs. AA + AT

TT

4.313

1.623

11.461

0.003

 PON1 rs662 GG vs. AA + AG

GG

9.800

1.179

81.451

0.035

 IFNL4 rs368234815 TT/TT vs. ∆G/TT + ∆G/∆G

TT/TT

2.600

1.427

4.734

0.002

 Chronic glomerulonephritis

Yes

0.432

0.220

0.851

0.015

The multivariate regression analysis

 Age at the RRT onset (years)

 

0.990

0.965

1.016

0.452

 RRT duration (years)

 

0.930

0.879

0.984

0.011

 PON1 rs854560 TT vs. AA + AT

TT

6.208

1.962

19.644

0.002

 PON1 rs662 GG vs. AA + AG

GG

10.762

1.222

94.796

0.032

 IFNL4 rs368234815 TT/TT vs. ∆G/TT + ∆G/∆G

TT/TT

2.607

1.298

5.235

0.007

 Chronic glomerulonephritis

Yes

0.609

0.259

1.432

0.255

  1. Hosmer Lemeshow goodness of fit P = 0. 949, Wald test P = 0.0001 for multivariate regression analysis