Paraoxonase 1 gene (PON1) variants concerning hepatitis C virus (HCV) spontaneous clearance in hemodialysis individuals: a case–control study

Table 3 An analysis of haplotype PON1 SNVs

SNVs	Haplotype	Freq	Case, control frequencies	Chi-square	P-value	P_corr value^a	OR (95%CI)^b, P-value	OR (95%CI)^c, P-value
rs662_rs854560	AA	0.391	0.318, 0.452	6.628	0.010	0.019	0.57 (0.37–0.88), 0.011	Reference
	AT	0.363	0.391, 0.340	0.998	0.318	0.629	1.22 (0.79–1.88), 0.366	1.60 (0.99–2.59), 0.057
	GA	0.223	0.256, 0.196	1.812	0.178	0.374	1.40 (0.86–2.30), 0.179	1.83 (1.05–3.18), 0.031
	GT	0.022	0.035, 0.012	2.121	0.145	0.304	3.72 (0.74–18.7), 0.088	5.09 (0.99–26.17), 0.032
rs854560_rs705379	AC	0.392	0.372, 0.408	0.482	0.487	0.843	0.85 (0.56–1.31), 0.466	Reference
	TT	0.304	0.325, 0.286	0.611	0.435	0.803	1.22 (0.77–1.91), 0.396	1.26 (0.76–2.09), 0.365
	AT	0.223	0.202, 0.240	0.735	0.391	0.756	0.81 (0.49–1.34), 0.415	0.94 (0.54–1.63), 0.816
	TC	0.082	0.101, 0.066	1.508	0.219	0.491	1.54 (0.72–3.31), 0.263	1.64 (0.73–3.67), 0.225
rs662_rs854560_rs705379	ATT	0.286	0.297, 0.276	0.189	0.663	0.997	1.13 (0.71–1.79), 0.611	Reference
	AAC	0.277	0.235, 0.312	2.628	0.105	0.372	0.69 (0.43–1.11), 0.123	0.70 (0.40–1.23), 0.214
	GAC	0.115	0.138, 0.096	1.564	0.211	0.670	1.49 (0.77–2.85), 0.233	1.30 (0.63–2.69), 0.475
	AAT	0.114	0.082, 0.140	2.961	0.085	0.314	0.55 (0.28–1.11), 0.093	0.54 (0.25–1.17), 0.115
	GAT	0.109	0.119, 0.100	0.322	0.570	0.984	1.19 (0.61–2.31), 0.616	1.07 (0.51–2.24), 0.860
	ATC	0.078	0.095, 0.064	1.172	0.279	0.794	0.49 (0.17–1.39), 0.171	1.30 (0.56–3.00), 0.541
	GTT	0.018	0.028, 0.010	1.462	0.227	0.696	3.13 (0.60–16.4), 0.155	2.81 (0.52–15.2), 0.212

ISSN: 1471-2334