| |
Standard care (n = 12)
|
Interferon (n = 44)
|
LPV/r plus interferon (n = 67)
|
Total patients (n = 123)
|
P-value
|
|---|
|
Any event
| | | | | |
|
Nausea
|
0
|
1 (2.27)
|
5 (7.46)
|
6 (4.88)
|
0.33
|
|
Diarrhea
|
0
|
4 (9.09)
|
11 (16.42)
|
15 (12.20)
|
0.20
|
|
Rash
|
0
|
2 (4.55)
|
2 (2.99)
|
4 (3.25)
|
0.72
|
|
Leukopenia
|
0
|
8 (18.18)
|
8 (11.94)
|
16 (13.01)
|
0.23
|
|
Neutropenia
|
0
|
6 (13.64)
|
6 (8.96)
|
12 (9.76)
|
0.35
|
|
Anemia
|
1 (8.33)
|
1 (2.27)
|
3 (4.48)
|
6 (4.88)
|
0.12
|
|
Thrombocytopenia
|
0
|
2 (4.55)
|
1 (1.49)
|
6 (4.88)
|
0.25
|
|
Increased creatinine
|
0
|
2 (4.55)
|
1 (1.49)
|
3 (2.44)
|
0.50
|
|
Increased aminotransferase
|
0
|
2 (4.55)
|
1 (1.49)
|
3 (2.44)
|
0.50
|
|
Increased bilirubin
|
1 (8.33)
|
2 (4.55)
|
9 (13.43)
|
12 (9.76)
|
0.30
|
|
Increased creatine kinase
|
0
|
7 (15.91)
|
14 (20.90)
|
21 (17.07)
|
0.20
|
