Table 4 Summary of adverse events in the enrolled patients
Standard care (n = 12) | Interferon (n = 44) | LPV/r plus interferon (n = 67) | Total patients (n = 123) | P-value | |
|---|---|---|---|---|---|
Any event | |||||
Nausea | 0 | 1 (2.27) | 5 (7.46) | 6 (4.88) | 0.33 |
Diarrhea | 0 | 4 (9.09) | 11 (16.42) | 15 (12.20) | 0.20 |
Rash | 0 | 2 (4.55) | 2 (2.99) | 4 (3.25) | 0.72 |
Leukopenia | 0 | 8 (18.18) | 8 (11.94) | 16 (13.01) | 0.23 |
Neutropenia | 0 | 6 (13.64) | 6 (8.96) | 12 (9.76) | 0.35 |
Anemia | 1 (8.33) | 1 (2.27) | 3 (4.48) | 6 (4.88) | 0.12 |
Thrombocytopenia | 0 | 2 (4.55) | 1 (1.49) | 6 (4.88) | 0.25 |
Increased creatinine | 0 | 2 (4.55) | 1 (1.49) | 3 (2.44) | 0.50 |
Increased aminotransferase | 0 | 2 (4.55) | 1 (1.49) | 3 (2.44) | 0.50 |
Increased bilirubin | 1 (8.33) | 2 (4.55) | 9 (13.43) | 12 (9.76) | 0.30 |
Increased creatine kinase | 0 | 7 (15.91) | 14 (20.90) | 21 (17.07) | 0.20 |