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Table 5 The positive predictive value and negative predictive value of the indices, alone and in combinations

From: Diagnostic value of combined pleural interleukin-33, adenosine deaminase and peripheral blood tuberculosis T cell spot detection TB for tuberculous pleurisy

Test method

Gold standard

Positive

Negative

IL-33

PPV 100.0%

Positive

28

0

NPV 43.1%

Negative

29

22

ADA

PPV 96.4%

Positive

53

2

NPV 83.3%

Negative

4

20

T-SPOT.TB

PPV 89.8%

Positive

53

6

NPV 80.0%

Negative

4

16

IL-33 + ADA

PPV 94.6%

Positive

53

3

NPV 82.6%

Negative

4

19

IL-33 + T-SPOT.TB

PPV 100.0%

Positive

44

0

NPV 62.9%

Negative

13

22

ADA + T-SPOT.TB

PPV 100%

Positive

48

0

NPV 71.0%

Negative

9

22

IL-33 + ADA + T-SPOT.TB

PPV 100.0%

Positive

50

0

NPV 75.9%

Negative

7

22

  1. The positive predictive value and negative value for IL-33, ADA, T-SPOT.TB were 100.0%, 43.1%; 96.4%, 83.3%; 89.8%, 80.0% respectively
  2. PPV positive predictive value, NPV negative predictive value