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Table 2 Univariate analyses with laboratory parameters in the outcomes in HIV/AIDS patients

From: Immunologic biomarkers, morbidity and mortality among HIV patients hospitalised in a Tertiary Care Hospital in the Brazilian Amazon

Laboratory tests Death Discharge p
N = 17 N = 66
Hematological data (NVA)
 HIV-RNA copies/mLb 126,578 (3247–273,012) 25,258.5 (391.5–145,976.8) 0.590
 Lymphocytes (percent)a (25.0–40.0%) 20.5 (10.3) 27.4 (13.5) 0.055
 CD4-T cells/µLb (600 to 1500/mm3) 44 (7–232) 79 (30–198.2) 0.140
 CD8-T cells/µLb (200 to 800/mm3) 402 (198–776) 544.5 (359.2–1143.8) 0.312
 CD4/CD8 ratiob (1.0 and 4.0) 0.1 (0–0.4) 0.1 (0.1–0.3) 0.123
 Hemoglobin (13.0–18.0 g/dL) 9.3 (2.7) 10.8 (2.4) 0.165
 Leukocytesb (4500–11,000/mL) 4740 (3510–8600) 4215 (3275–5,757.5) 0.527
 Neutrophilsb (1800–7700/mL) 2660 (1679–3234) 3118 (2109–4907.5) 0.113
 Monocytesb (80–1100/mL) 249 (161–379) 329 (187.2–488.2) 0.370
 Eosinophilsb (40–550/mL) 2 (2–4) 4 (2.6–7) 0.030*
 Plateletsa (150,000–400,000 × 103/mL) 299,352.9 (207,630.4) 273,947.0 (132,454.6) 0.536
 MPVb (8.8 fL to 12.5 fL) 8.2 (7.8–8.8) 8.1 (7.4–8.7) 0.446
 PDWb (9.3 fL to 16.0 fL) 15.8 (13–18.7) 13.5 (11.2–16.5) 0.037*
Biochemistry parameters (NVA)
 Bilirubinb (< 1.0 mg/dL) 0.4 (0.2–0.9) 0.4 (0.3–0.7) 0.999
 Creatinineb (0.6–1.35 mg/dL) 1 (0.7–1.3) 0.8 (0.6–0.9) 0.069
 LDHb (120 and 246 U/uL) 435 (332–534) 367.5 (300.2–474.2) 0.159
 Gamma-glutamyltransferaseb,c 88 (42–203) 103.5 (57.8–290) 0.876
 Albuminb (3.5–5.0 g/dL) 3.4 (2.8–4) 3.8 (3.3–4.5) 0.129
 Alkaline phosphataseb (65.0–330.0 U/uL) 282 (200–459) 281 (201–386) 0.835
 Aspartate aminotransferaseb (2–38.0 U/uL) 44 (26–82) 34 (25–58) 0.280
 Alanine aminotransferaseb (2–44.0 U/uL) 31 (22–41) 43 (31–77) 0.038*
  1. NVA Normal values in adults, PDW Platelet distribution width, MPV Mean platelet volume, LDH lactate dehydrogenase
  2. aMean and standard
  3. bMedian (25th; 75th interquartile)
  4. cReferences values of Gamma-glutamyltransferase (men: 10 to 50 U/uL and women: 7 to 32 U/uL)
  5. *, **: p-value; statistically significant difference