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Table 3 Data extraction of findings (except where specified, results are presented as Int. group vs. Cont. group)

From: Effectiveness of mobile text reminder in improving adherence to medication, physical exercise, and quality of life in patients living with HIV: a systematic review

Study

Timepoint

Medication adherence and outcome

Physical activity adherence and outcome

Quality of life and outcome

Gross et al. (2019) [23]

Immediately post-intervention at week 48

100%: Using self-reported adherence n (%):

[Int. 174(73) vs. Cont. 173(69)]; p = 0·89

  

Ruan et al. (2017) [20]

Immediately post-intervention at month 6

100%: Using CPCRA adherence n (%):

[Int. 42(89.3) vs. Cont. 34(72.3)]; Z = 2.208; p = 0.027

80%-99% Using CPCRA adherence n (%):

[Int. 3(6.4) vs. Cont. 3(6.4)]; Z = 2.208; p = 0.027

 < 79% Using CPCRA adherence n (%):

[Int. 2(4.3) vs. Cont. 10(21.3)]; Z = 2.208; p = 0.027

Using Visual Analogue Scale (VAS) mean ± SD:

[Int. (98.72 ± 2.35) vs. Cont. (93.11 ± 6.51)]; Z = 2.735; p = 0.006

  

Nsagha et al. (2016) [26]

Immediately post-intervention at week 4

Using the interviewer-administered self-report questionnaire %:

[Int. 64.4% vs. Cont. 44.2%] Z = NR; p = 0.05

  

Sabin et al. (2015) [27]

Immediately post-intervention at month 9 following 3 months of pre-intervention

Using wise-pill device mean ± SD:

[Int. (96.2 ± 6.4) vs. Cont. (89.1 ± 15.9)]; Z = NR; p = 0.003

  

Moore et al. (2015) [24]

Immediately post-intervention at day 30

Using MEMS mean ± SD::

[Int. (86.2 ± 12.7) vs. Cont. (84.8 ± 18.1)]; cliff’s d = 0.01; p = 0.95

Using self-reported VAS mean ± SD:

[Int. (95.8 ± 6.6) vs. Cont. (92.4 ± 13.0)]; Z = NR; p = 0.44

  

Maduka and Tobin-West., (2013) [22]

Immediately post-intervention at month 4

Using self-reported adherence questionnaire n (%):

[Int. 40(76.9) vs. Cont. 29(55.8)]; Z = 0.224; p = 0.022

  

Mbuagbaw et al. (2012) [21]

Immediately post-intervention at month 6

Using Visual Analogue Scale (VAS) n (%):

[Int. 72(71.3) vs. Cont. 66(66.7)]; Z = NR; p = 0.542

Using self-report n (%):

[Int. 80(79.2) vs. Cont. 78(79.0)]; Z = NR; p =  > 0.999

Using pharmacy refill data mean ± SD:

[Int. (3.8 ± 1.48) vs. Cont. (3.7 ± 1.34)]; Z = NR; p = 0.617

 

Using SF-12 scale score Quality of life assessment form:

[Int. (3.79 ± 0.585) vs. Cont. (3.75 ± 0.583)]; Z = NR; p = 0.629

da Costa et al. (2012) [18]

Immediately post-intervention at month 4

Using self-reported adherence n (%):

[Int. 8(100.00) vs. Cont. 12(92.31)]; Z = 0.8038; p = 0.4215

Using pill counting n (%):

[Int. 5(62.50) vs. Cont. 6(46.15)]; Z = 0.7284; p = 0.4664

Using micro-electronic monitoring systems (MEMS) n (%):

[Int. 6(75.00) vs. Cont. 7(53.85)]; Z = 0.9694; p = 0.3324

  

Pop-eleches et al. (2011) [25]

Immediately post-intervention at week 48

Using the medication event monitoring system (MEMS) n/N:

4 intervention groups (daily short messages, weekly short messages, daily long messages and weekly long messages) with the control group

Summary group (All daily reminder groups, irrespective of message length):

[Int. 0.41 vs. Cont. 0.40]; Z = NR; p = 0.92

Summary group (All weekly reminder groups, irrespective of message length):

[Int. 0.53 vs. Cont. 0.40]; Z = NR; p = 0.03

Summary group (All short reminder groups, irrespective of message frequency):

[Int. 0.47 vs. Cont. 0.40]; Z = NR; p = 0.27

Summary group (All long reminder groups, irrespective of message frequency):

[Int. 0.47 vs. Cont. 0.40]; Z = NR; p = 0.24

Subgroups

Subgroup 1 (daily short messages):

[Int. 0.40 vs. Cont. 0.40]; Z = NR; p = 0.97

Subgroup2 (weekly short messages):

[Int. 0.53 vs. Cont. 0.40]; Z = NR; p = 0.07

Subgroup3 (daily long messages):

[Int. 0.42 vs. Cont. 0.40]; Z = NR; p = 0.85

Subroup4 (weekly long messages):

[Int. 0.53 vs. Cont. 0.40]; Z = NR; p = 0.08

  

Lester et al. (2010) [19]

Immediately post-intervention

Using self-reported questionnaire n (%):

[Int. 168(62) vs. Cont. 132(50)]; Z = NR; p = 0.006

  
  1. Int. intervention group, Cont. control group, p p value, n number of participants, N total number of participants, Subgroup1 daily, short SMS, Subgroup2 weekly, short SMS, Subgroup3 daily, long SMS, Subgroup4 weekly, long SMS, SMS short message service, NS not significant, NR not reported, CPCRA community programs for clinical research on AIDS adherence self-report questionnaire