Table 6 Comparison of demographic and clinical characteristics between survivors and non-survivors
Characteristics | Total (N = 72) | Survivors (N = 50) | Non-Survivors (N = 22) | P |
|---|---|---|---|---|
Age (years) | 49.7 ± 18.3 | 45.5 ± 17.8 | 59.0 ± 16.3 | 0.003 |
Age > 50 | 41 | 23 | 18 | 0.005 |
Sex | ||||
 Male | 54 (75.0) | 36 (72.0) | 18 (81.8) | 0.375 |
 Female | 18 (25.0) | 14 (28.0) | 4 (18.2) | |
Days in hospital | 29.5 (19.3–46.0) | 29.0 (20.7–45.0) | 33.5 (18.0–51.0) | 0.633 |
Comorbidity | ||||
 Pulmonary infection | 35 (48.6) | 15 (30.0) | 20 (90.9) | < 0.001 |
 Hypertension | 29 (40.3) | 16 (32.0) | 13 (59.1) | 0.031 |
 Hydrocephalus | 26 (36.1) | 16 (32.0) | 10 (45.5) | 0.274 |
 Intracranial hemorrhage | 19 (26.4) | 13 (26.0) | 6 (27.3) | 0.91 |
 Diabetes | 10 (13.9) | 5 (10.0) | 5 (22.7) | 0.285 |
 MDR bacteria infection | 49 (68.1) | 31 (62.0) | 18 (81.8) | 0.097 |
 Glucocorticoid therapy > 3 days | 29 (40.3) | 18 (36.0) | 11 (50.0) | 0.265 |
Surgery | ||||
 Yes | 50 (69.4) | 33 (66.0) | 17 (77.3) | 0.339 |
 No | 22 (30.6) | 17 (34.0) | 5 (22.7) | |
Invasive device | ||||
 External ventricular drainage/Lumbar cistern drainage | 41 (56.9) | 25 (50.0) | 16 (72.7) | 0.073 |
 Catheter | 57 (79.2) | 37 (74.0) | 20 (90.9) | 0.189 |
CSF data | ||||
 ADA level (U/L) | 15.50 (4.33–30.95) | 14.00 (3.30–28.25) | 19.55 (5.48–37.48) | 0.131 |
 Glucose level (mmol/L) | 1.71 (0.21–2.98) | 2.29 (1.35–3.46) | 0.35 (0.05–0.91) | < 0.001 |
 Chlorine level (mmol/L) | 116.68 ± 9.27 | 117.16 ± 8.67 | 115.58 ± 10.63 | 0.508 |
 Protein level (g/L) | 2.37 (1.12–4.01) | 1.67 (0.84–2.78) | 4.00 (2.98–4.54) | < 0.001 |
 Leukocyte count (× 106/L) | 340.0 (52.5–2400.0) | 188.0 (27.5–927.5) | 1125.0 (102.5–4185.0) | 0.029 |
 Erythrocyte count (× 106/L) | 395.0 (10.0–4787.5) | 395.0 (7.5–1987.5) | 810.0 (65.0–10,675.0) | 0.306 |
Blood data | ||||
 White blood cell level (× 109/L) | 13.13 ± 6.11 | 12.42 ± 5.64 | 14.75 ± 6.94 | 0.138 |
 Neutrophils level (× 109/L) | 10.55 (6.94–13.48) | 10.13 (6.58–12.68) | 12.56 (8.68–14.85) | 0.071 |
 Percentage of neutrophils | 85.21 (78.86–88.05) | 84.35 (76.36–87.49) | 87.14 (83.40–88.88) | 0.039 |
Liver function | ||||
 ALT (U/L) | 22.80 (14.63–57.93) | 20.80 (14.08–46.35) | 36.60 (19.40–125.15) | 0.018 |
 AST (U/L) | 22.60 (17.03–39.45) | 20.05 (15.53–38.03) | 31.80(19.25–66.28) | 0.014 |
 TBIL (mmol/L) | 14.65 (10.13–18.60) | 13.90 (9.40–18.30) | 15.05 (12.88–21.48) | 0.167 |
 ALP (U/L) | 89.5 (72.0–127.0) | 82.0 (70.5–118.0) | 104.0 (77.8–170.5) | 0.069 |
 Total protein (g/L) | 63.22 ± 8.06 | 64.30 ± 8.04 | 60.76 ± 7.73 | 0.086 |
 Albumin (g/L) | 35.93 ± 6.62 | 37.75 ± 5.51 | 31.79 ± 7.15 | < 0.001 |
Renal function | ||||
 Urea nitrogen (mmol/L) | 5.05 (3.58–6.95) | 4.72 (2.98–6.58) | 6.13 (4.63–8.60) | 0.02 |
 Creatinine (mmol/L) | 61.53 ± 25.25 | 61.27 ± 27.27 | 62.14 ± 20.51 | 0.893 |