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Table 1 Comparison of variables between HIV/TB patients and HIV/non-TB patients by univariate analysis

From: The development and validation of a diagnostic scoring system to differentiate pulmonary tuberculosis from non-tuberculosis pulmonary infections in HIV-infected patients with severe immune suppression

Variables

HIV/TB patients (n = 288)

HIV/non-TB patients

Z/F

p

Viral infection (n = 23)

Fungal infection (n = 163)

Bacterial infection (n = 124)

Total (n = 310)

Demographic

 Age (years)

43.73 ± 13.43

46.17 ± 8.98

45.55 ± 14.88

48.92 ± 14.04

46.94 ± 14.24

2.897

0.005

 Male (n, %)

238(82.6%)

18(78.0%)

125 (76.7%)

96 (77%)

239 (77.1%)

2.841

0.092

Laboratory

 WBC (109 cells/L)

6.11 ± 3.27

4.80 ± 1.77

5.55 ± 5.07

6.23 ± 3.59

5.77 ± 4.35

1.074

0.283

 HGB (g/L)

98.66 ± 20.76

117.78 ± 24.94

113.31 ± 21.94

110.67 ± 25.63

112.59 ± 23.70

7.618

0.000

 PLT (109 cells/L)

201.16 ± 107.07

176.39 ± 110.85

218.09 ± 103.28

196.85 ± 90.75

206.50 ± 99.60

0.631

0.528

 ALB (g/L)

32.54 ± 6.01

39.39 ± 5.20

34.83 ± 6.86

34.87 ± 6.46

35.19 ± 6.68

5.082

0.000

 CD4+ T-cell count (cells/μl)

45 (1–591)

86 (6–669)

25 (1–504)

54.5 (2–1252)

37 (1–1252)

1.324

0.186

  < 200

267(92.7%)

16(69.6%)

155(95.1%)

103(83.1%)

274(88.4%)

3.233

0.094

  ≥ 200

21(7.3%)

7(30.4%)

8(4.9%)

21(16.9%)

36(11.6%)

  

 HIV RNA (log10 copies/mL)

5.00 ± 1.43

3.89 ± 1.71

4.99 ± 1.15

4.26 ± 1.75

4.62 ± 1.51

1.900

0.257

 ESR (mm/h)

75.31 + 42.62

51.50 ± 40.81

70.39 ± 34.80

58.69 ± 39.93

48.42 + 42.86

7.681

0.000

 PCT (ng/ml)

0.15(0–73.99)

0.12(0–0.3)

0.14 (0.01–18.62)

0.12 (0.01–2.98)

0.09(0–18.62)

5.876

0.008

Symptoms

 Weight loss (Kg)

3(0–25)

2(0–10)

3(0–20)

3(0–20)

3(0–20)

1.689

0.091

 Fever (n, %)

225(78.1%)

12 (52.2%)

94 (57.7)

74 (60%)

180 (58.1%)

27.487

0.000

 Highest body temperature (°C)

38.79 ± 1.29

37.37 ± 0.95

37.89 ± 1.15

37.92 ± 1.12

37.86 ± 1.13

9.400

0.000

CT scan

 Number of infected pulmonary lobes (n)

5(0–5)

2 (0–5)

2 (0–5)

3 (0–5)

3 (0–5)

8.665

0.000

 Opacities (n, %)

250(86.8%)

22 (95.7%)

128 (78.5%)

106 (85%)

256 (82.6%)

2.047

0.152

 Solid lesion (n, %)

126(43.8%)

6 (26.1%)

43 (26%)

57 (46%)

106 (34.2%)

5.742

0.017

 Pulmonary cavitation (n, %)

36(12.5%)

0 (0%)

4 (2%)

5 (4%)

9 (2.9%)

19.759

0.000

 Pleural effusion (n, %)

150(52.1%)

0 (0%)

29 (18%)

11 (9%)

40 (12.9%)

105.724

0.000

 Cervical lymphadenopathy (n, %)

33(11.5%)

1 (4.3%)

5 (3%)

4 (3%)

10 (3.2%)

15.162

0.000

 Axillary lymphadenopathy (n, %)

11(3.8%)

3 (13.0%)

2 (1.2%)

1 (0.8%)

6 (1.9%)

1.919

0.166

 Inguinal lymphadenopathy (n, %)

10(3.5%)

0

5 (3.1%)

1 (0.8%)

6 (1.9%)

1.354

0.245

 Hilar and/or mediastinal lymphadenopathy (n, %)

212(73.6%)

1 (4.3%)

47 (29%)

44 (35%)

92 (29.7%)

115.3

0.000

 Pericardial effusion (n, %)

37(12.8%)

2 (8.6%)

8 (5%)

3 (2%)

13 (4.2%)

14.592

0.000

 Miliary nodules (n, %)

76(26.4%)

0 (0%)

2 (1%)

0 (0%)

2 (0.6%)

87.237

0.000

  1. WBC white blood cell, HGB hemoglobin, PLT platelet, ALB albumin, ESR erythrocyte sedimentation rate, PCT procalcitonin