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Table 1 Comparison of variables between HIV/TB patients and HIV/non-TB patients by univariate analysis

From: The development and validation of a diagnostic scoring system to differentiate pulmonary tuberculosis from non-tuberculosis pulmonary infections in HIV-infected patients with severe immune suppression

Variables HIV/TB patients (n = 288) HIV/non-TB patients Z/F p
Viral infection (n = 23) Fungal infection (n = 163) Bacterial infection (n = 124) Total (n = 310)
Demographic
 Age (years) 43.73 ± 13.43 46.17 ± 8.98 45.55 ± 14.88 48.92 ± 14.04 46.94 ± 14.24 2.897 0.005
 Male (n, %) 238(82.6%) 18(78.0%) 125 (76.7%) 96 (77%) 239 (77.1%) 2.841 0.092
Laboratory
 WBC (109 cells/L) 6.11 ± 3.27 4.80 ± 1.77 5.55 ± 5.07 6.23 ± 3.59 5.77 ± 4.35 1.074 0.283
 HGB (g/L) 98.66 ± 20.76 117.78 ± 24.94 113.31 ± 21.94 110.67 ± 25.63 112.59 ± 23.70 7.618 0.000
 PLT (109 cells/L) 201.16 ± 107.07 176.39 ± 110.85 218.09 ± 103.28 196.85 ± 90.75 206.50 ± 99.60 0.631 0.528
 ALB (g/L) 32.54 ± 6.01 39.39 ± 5.20 34.83 ± 6.86 34.87 ± 6.46 35.19 ± 6.68 5.082 0.000
 CD4+ T-cell count (cells/μl) 45 (1–591) 86 (6–669) 25 (1–504) 54.5 (2–1252) 37 (1–1252) 1.324 0.186
  < 200 267(92.7%) 16(69.6%) 155(95.1%) 103(83.1%) 274(88.4%) 3.233 0.094
  ≥ 200 21(7.3%) 7(30.4%) 8(4.9%) 21(16.9%) 36(11.6%)   
 HIV RNA (log10 copies/mL) 5.00 ± 1.43 3.89 ± 1.71 4.99 ± 1.15 4.26 ± 1.75 4.62 ± 1.51 1.900 0.257
 ESR (mm/h) 75.31 + 42.62 51.50 ± 40.81 70.39 ± 34.80 58.69 ± 39.93 48.42 + 42.86 7.681 0.000
 PCT (ng/ml) 0.15(0–73.99) 0.12(0–0.3) 0.14 (0.01–18.62) 0.12 (0.01–2.98) 0.09(0–18.62) 5.876 0.008
Symptoms
 Weight loss (Kg) 3(0–25) 2(0–10) 3(0–20) 3(0–20) 3(0–20) 1.689 0.091
 Fever (n, %) 225(78.1%) 12 (52.2%) 94 (57.7) 74 (60%) 180 (58.1%) 27.487 0.000
 Highest body temperature (°C) 38.79 ± 1.29 37.37 ± 0.95 37.89 ± 1.15 37.92 ± 1.12 37.86 ± 1.13 9.400 0.000
CT scan
 Number of infected pulmonary lobes (n) 5(0–5) 2 (0–5) 2 (0–5) 3 (0–5) 3 (0–5) 8.665 0.000
 Opacities (n, %) 250(86.8%) 22 (95.7%) 128 (78.5%) 106 (85%) 256 (82.6%) 2.047 0.152
 Solid lesion (n, %) 126(43.8%) 6 (26.1%) 43 (26%) 57 (46%) 106 (34.2%) 5.742 0.017
 Pulmonary cavitation (n, %) 36(12.5%) 0 (0%) 4 (2%) 5 (4%) 9 (2.9%) 19.759 0.000
 Pleural effusion (n, %) 150(52.1%) 0 (0%) 29 (18%) 11 (9%) 40 (12.9%) 105.724 0.000
 Cervical lymphadenopathy (n, %) 33(11.5%) 1 (4.3%) 5 (3%) 4 (3%) 10 (3.2%) 15.162 0.000
 Axillary lymphadenopathy (n, %) 11(3.8%) 3 (13.0%) 2 (1.2%) 1 (0.8%) 6 (1.9%) 1.919 0.166
 Inguinal lymphadenopathy (n, %) 10(3.5%) 0 5 (3.1%) 1 (0.8%) 6 (1.9%) 1.354 0.245
 Hilar and/or mediastinal lymphadenopathy (n, %) 212(73.6%) 1 (4.3%) 47 (29%) 44 (35%) 92 (29.7%) 115.3 0.000
 Pericardial effusion (n, %) 37(12.8%) 2 (8.6%) 8 (5%) 3 (2%) 13 (4.2%) 14.592 0.000
 Miliary nodules (n, %) 76(26.4%) 0 (0%) 2 (1%) 0 (0%) 2 (0.6%) 87.237 0.000
  1. WBC white blood cell, HGB hemoglobin, PLT platelet, ALB albumin, ESR erythrocyte sedimentation rate, PCT procalcitonin