Fig. 1

a Positron emission computed tomography of patient 1 revealing abnormal uptake in the lung lesions (SUVmax = 4.3), mediastinal lymph nodes (SUVmax = 14.5), cervical lymph nodes (SUVmax = 2.7), left adrenal gland (SUVmax = 3.6), cervical spine (SUVmax = 10.0) and para-aortic lymph nodes (SUVmax = 3.8). b Chest CT of patient 2 showing lobularinflammation. c Left cervical lymph node specimens from patient 2 showing chronic granulomatous inflammation of the lymph nodes with caseous necrosis. d Fiberoptic bronchoscopy in patient 2 showing three small nodules fused with each other at the left main bronchus. e Chest CT of patient 3 showing pericardial effusion. f Fiberoptic bronchoscopy in patient 3 showing a subcarinal tuberosity. g Fiberoptic bronchoscopy in patient 4 showing a nodule in the left sub-bronchus. h ECT of patient 4 revealing active bony metabolismin the right sacroiliac joint