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Table 6 Clinical predictors of neuritis and neuropathic pain (n = 124)

From: Clinical prediction rules for the diagnosis of neuritis in leprosy

Variable Neuritis N (%) Neuropathic pain N (%) p-Value1
Date of pain onset (2 categories)
 Up to 90 days ago 10 (50.0) 27 (26.0) 0.031
 > 90 days 10 (50.0) 77 (74.0)
Sense of numbness
 No 7 (35.0) 22 (21.2) 0.1912
 Yes (< 30 days) 2 (10.0) 5 (4.8)
 Yes (≥ 30 days) 11 (55.0) 77 (74.0)
Sense of paraesthesia
 No 5 (25.0) 29 (27.9) 0.4542
 Yes (< 30 days) 2 (10.0) 4 (3.8)
 Yes (≥ 30 days) 13 (65.0) 71 (68.3)
Sense of weakness
 No 9 (45.0) 33 (31.7) 0.2632
 Yes (< 30 days) 2 (10.0) 6 (5.8)
 Yes (≥ 30 days) 9 (45.0) 65 (62.5)
Motor difficulties
 No 5 (25.0) 26 (25.0) 0.7062
 Yes (< 30 days) 1 (5.0) 3 (2.9)
 Yes (≥ 30 days) 14 (70.0) 75 (72.1)
Sensory symptoms
 No 3 (15.0) 15 (14.4) 0.4722
 Yes (< 30 days) 1 (5.0) 4 (3.8)
 Yes (≥ 30 days) 16 (80.0) 85 (81.7)
Motor symptoms
 No 5 (25.0) 13 (12.5) 0.2772
 Yes (< 30 days) 1 (5.0) 5 (4.8)
 Yes (≥ 30 days) 14 (70.0) 86 (82.7)
Neurological symptoms
 No 3 (15.0) 3 (2.9) 0.1032
 Yes (< 30 days) 1 (5.0) 5 (4.8)
 Yes (≥ 30 days) 16 (80.0) 96 (92.3)
Worse in the morning
 No 11 (55.0) 64 (61.5) 0.584
 Yes 9 (45.0) 40 (38.5)
Worse at night
 No 7 (35.0) 44 (42.3) 0.543
 Yes 13 (65.0) 60 (57.7)
Worse upon movement
 No 6 (30.0) 57 (54.8) 0.042
 Yes 14 (70.0) 47 (45.2)
Worse with physical exertion
 No 6 (30.0) 35 (33.7) 0.750
 Yes 14 (70.0) 69 (66.3)
Triggered by nerve palpation
 No 4 (20.0) 53 (51.0) 0.039
 Yes, spontaneously declared 9 (45.0) 28 (26.9)
 Yes, declared after questioning 7 (35.0) 23 (22.1)
Irradiated pain
 No 6 (30.0) 37 (35.6) 0.631
 Yes 14 (70.0) 67 (64.4)
  1. 1Pearson Chi-square test; 2Fisher’s exact test