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Table 1 Outcome measures

From: Action for better brain health among people living with HIV: protocol for a randomized controlled trial

Outcome

Measure

Value

Confirmatory outcomes

Primary 1: uptake of the recommendations for physical activity

Number of physical activity-weeks. Recorded by Garmin VivoFit 4

Number of weeks in which physical activity guidelines are met (150 min of moderate to vigorous activity in bouts of 10 min) [42]

Primary 2: uptake of the recommendations for social activity

Number of social activity-weeks. Recorded by pictures provided by participants

Number of weeks in which at least one social activity was attended

Explanatory outcomes

Achievement of personal goals

Goal attainment scaling [40, 43]

Recorded on the goal-setting app

N and diversity of goals set and met

Physical activity pattern

Daily step counts, time spent in cadence bands for moderate (100 steps/min) and vigorous (130 steps/min) intensity [44], sitting time. Recorded by the Garmin VivoFit 4

Trajectory of weekly cumulative step counts (rising, stable, falling)

Trajectory of weekly cumulative sitting time (rising, stable, falling)

General Health perception, sleep, distress, pain, fatigue, depression, anxiety, quality of life

Visual Analogue Health States [45]

0–10 for each

Downstream health outcomes (platform measures)

Mood

RAND-36 Mental Health Inventory [46]

0–100

Energy/fatigue

RAND-36 Vitality [46]

0–100

Physical function

RAND-36 Physical Function Inventory [46] and five-repetition sit-to-stand test [47]

0–100; time in seconds

Performance based-report cognitive ability

Brief Cognitive Ability Measure (B-CAM) [48]

0–35 English / 42 French

Self-report cognitive ability

Communicating Cognitive Concerns Questionnaire (C3Q) [37]

0–36

Health related quality of life

EuroQol Five Dimensions Questionnaire (EQ-5D) [49], Patient Generated Index [50, 51]

0–1; 0–100

Improved vascular risk profile

Framingham Cardiovascular Disease Risk Score [52, 53]

Probability of stroke

Social network size

Social network size and quality [54]

0–100