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Table 2 Bivariate and multivariate logistic regression for factors associated with inappropriate PI prescription during rifampicin-based TB treatment

From: Adoption of evidence-informed guidelines in prescribing protease inhibitors for HIV-Tuberculosis co-infected patients on rifampicin and effects on HIV treatment outcomes in Uganda

 

Crude Odds ratio (95% CI)

P value

Adjusted Odds ratio (95% CI)

P value

Cadre of prescribing clinician

 Clinical officer

1

 

1

 

 Doctor

0.22 (0.13–0.36)

 < 0.001

0.26 (0.15–0 .46)

< 0.001

 Nurse

0.27 (0.15–0.47)

 < 0.001

0.35 (0.18–0 .71)

0.003

Clinic level

 KCCA

1

 

1

 

 RRH

2.08 (1.26–4.18)

0.004

1.10 (0.60–2.03)

0.760

Age (years)

  < 25

1

 

1

 

 25–34

0.87 (0.47–1.59)

0.657

0.86 (0.42–1.76)

0.679

 35–44

1.04 (0.56–1.91)

0.889

0.97 (0.47–2.01)

0.939

 45–54

1.48 (0.69–3.16)

0.310

1.24 (0.52–2.96)

0.629

 55–64

0.29 (0.11–0.76)

0.012

0.33 (0.11–1.02)

0.053

Weight (kg)

  < 33

1

 

1

 

 33–39

1.41 (0.47–4.21)

0.534

1.10 (0.33–3.70)

0.878

 40–54

2.14 (0.89–5.10)

0.086

1.95 (0.71–5.38)

0.197

 55–70

1.88 (0.77–4.61)

0.164

1.78 (0.59–5.32)

0.305

  > 70

0.62 (0.20–1.90)

0.402

0.49 (0.12–1.94)

0.310

Duration on PI before TB treatment

 PI and TB treatment started the same day

1

 

1

 

  < 1 year

1.35 (0.81–2.27)

0.245

1.01 (0.58–1.77)

0.975

 1 year–≤ 2 years

2.41 (1.21–4.80)

0.012

1.45 (0.69–3.05)

0.322

  > 2 years

2.96 (1.57–5.55)

0.001

1.56 (0.77–3.16)

0.216

  1. KCCA Kampala City Council Authority, RRH Regional Referral Hospital, inappropriate PI prescription  prescription of LPV/r 400/100 mg BID or a prescription of ATV/r