Fig. 2

Acylcarnitines were identified as the metabolites exhibiting the main differences between IR and INR. a Metabolite Set Enrichment Analysis using 18 metabolites which could distinguish controls, IR, and INR. b Box-and-whisker plots of the metabolite levels in control (n = 18), IR (n = 10), and INR (n = 10) samples. ANOVA with Fisher’s LSD test (FDR < 5%) was used to compare the three groups. *p < 0.05, **p < 0.01, ***p < 0.001