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Table 4 Demographic and clinical presentations of MRSA and V. vulnificus associated necrotizing fasciitis patients

From: Bacteriology and mortality of necrotizing fasciitis in a tertiary coastal hospital with comparing risk indicators of methicillin-resistant Staphylococcus aureus and Vibrio vulnificus infections: a prospective study

Characteristics MRSA
(N-16)
Vibrio vulnificus
(N-40)
p-value
Age (years)    
 Mean 62.8 71.2 0.35
Gender    
 Female 5 14 0.52
 Male 11 26
Comorbidities (%)    
 Hepatic dysfunction 5 (31.2) 25 (62.5) 0.034*
 LC alone or with others 3 (18.75) 7 (17.5) 1
 Diabetic mellitus 8 (50) 12 (20) 0.136
 Cancer 2 (12.5) 2 (5) 0.321
 Chronic kidney disease 4 (25) 10 (25) 0.624
Interval from contact or injury 5.5 1.2 0.023*
to presentation at ER (days)    
Interval from diagnosis at ER 5.8 4.7 0.53
to first operation (hours)    
Wound location (%)    
 Upper extremity 8 (50) 24 (60) 0.489
 Lower extremity 8 (50) 16 (40)
Outcome 6.25% 10%  
 Death 1 4 0.383
 Survivors 15 36
Related events (%)    
 Seawater or seafood contact 2 (12.5) 37 (92.5) 0.001*
 Farm/dirty-water contacted 1 (6.25) 3 (7.5) 0.43
Vital signs (%)    
 Body temperature > 38 °C 4 (25) 8 (20) 0.376
 Heart rate ≥ 100 10 (62.5) 22 (55) 0.607
 Respiratory rate > 20 7 (43.75) 23 (57.5) 0.325
 Systolic blood pressure < 90 0 9 (22.5) 0.036*
Cultures (%)    
 Blood (P) Wound (P) 3 (18.75) 15 (37.5)  
 Blood (P) Wound (N) 0 11 (27.5)  
 Blood (N) Wound (P) 13 (81.25) 14 (35)  
Presence of bacteremia (%) 3 (18.75) 26 (65) 0.002*
  1. Blood (P), culture-positive blood sample; Blood (N), culture-negative blood sample; Wound (P), culture-positive surgical wound sample; Wound (N), culture-negative surgical wound sample
  2. Hepatic dysfunction included liver cirrhosis (LC), hepatitis B or C, hepatocellular carcinoma, and alcoholic liver disease
  3. *Mean p < 0.05 and the difference was significant