Evaluation of the added value of viral genomic information for predicting severity of influenza infection

BMC Infectious Diseases

Table 1 Characteristics of patients hospitalized for severe acute respiratory infection (SARI) (n = 160), stratified per severity status, i.e. severe influenza A(H3N2) infections (cases) and non-severe influenza A(H3N2) infections (controls), Belgium, Influenza season 2016–2017

	Severe SARI patients (i.e., cases) (n = 38)		Non-severe SARI patients (i.e., controls) (n = 122)		p value^a
	Median + IQR	Total	Median + IQR	Total
Age (years)	77.5 (67.5–82)	38	77.5 (61–84)	122	0.94
Sampling period (weeks)	5 (4.25–6)	38	5 (4–6)	122	0.31
	Proportion	Total	Proportion	Total
Males	0.54	37	0.48	119	0.58
Vaccinated	0.53	19	0.34	71	0.18
Chronic cardiovascular condition	0.47	38	0.29	122	0.047
Chronic respiratory condition	0.39	38	0.20	122	0.02
Renal insufficiency	0.34	38	0.16	122	0.02
Hepatic insufficiency	0.03	38	0.04	122	> 0.99
Immunocompromised condition	0.26	38	0.10	122	0.02
Pregnant	0.00	38	0.02	122	/
Asthma	0.00	38	0.06	122	/
Neuromuscular condition	0.11	38	0.12	122	> 0.99
Diabetes	0.18	38	0.15	122	0.61
Obesity	0.08	38	0.11	122	0.76

SARI severe acute respiratory infection, IQR interquartile range
^aWilcoxon rank sum test applied for medians and Fisher’s exact test applied for proportions

ISSN: 1471-2334