Table 1 Characteristics of studies included in the systematic review and meta-analysis of TTIs among blood donors in Ethiopia
First Author | Publication year | Sampling year | Study Design | Blood donor type | Setting | Sample Size | Blood donor by sex | HIV | HBV | HCV | Syphilis | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Male | Female | HIV reactive | HIV Diagnosis method | HBVsAg reactive | HBVSAg Diagnosis method | Anti-HCV reactive | Anti-HCV Diagnosis Method | Syphilis Reactive | Syphilis Diagnosis Method | |||||||
Asrie F et al. | 2016 | 2015 | Prospective | – | North Gondar | 558 | 351 | 207 | 1.4%(8/558) | 4th Gen ELISA | 3.9% (22/558) | 4th Gen ELISA | 1.8% (10/558) | 4th Gen ELISA | – | – |
Teklemariam Z, et al. | 2018 | 2008–2015 | Retrospective | Both | Harar | 11,382 | 9403 | 1978 | 0.6%(69/11382) | ELISA | 4.4% (5001/11382) | ELISA | 0.8% (91/11382) | ELISA | 1.6% (182/11382) | ELISA |
Habte Y et al. | 2016 | 2009–2014 | Retrospective | Both | Dire Diwa | 4157 | 3434 | 723 | – | – | 3.73% (155/4157) | – | – | – | – | – |
Sharew B et al. | 2017 | 2008–2012 | Retrospective | Both | Desie | 9384 | 7514 | 1870 | 5.1%(476/9384) | 4th Gen ELISA | – | – | – | – | – | – |
Diressa T et al. | 2018 | 2014–2017 | Retrospective | Both | North Shewa | 8460 | 5644 | 2816 | 0.25%(21/8460) | 4th Gen ELISA | 1.2% (103/8460) | 4th Gen ELISA | 0.32% (27/8460) | ELISA | 0.71% (60/8460) | TPHA |
Seyoum E, et al. | 2005 | 2003 | Prospective | – | Addis Ababa | 408 | – | – | 4.2%(17/408) | – | – | – | – | – | – | – |
Ambachew H, et al. | 2018 | 2016 | Prospective | – | Hawassa | 2237 | – | – | 1.7%(38/2237) | 4th Gen ELISA | 4.7% (106/2237) | 4th Gen ELISA | 0.5% (11/2237) | ELISA | 0.5% (11/2237) | ELISA |
Degefa B et al. | 2018 | 2011–2014 | Retrospective | Both | Mekelle | 10,728 | 3750 | 6978 | 1.03%(111/10728) | 4th Gen ELISA | 3.8% (407/10728) | 4th Gen ELISA | 1.33% (143/10728) | ELISA | – | – |
Abate M et al. | 2016 | 2010–2014 | Retrospective | Both | Jigjiga | 6827 | 6648 | 179 | 3.16%(216/6827) | 4th Gen ELISA | 9.48% (647/6827) | 4th Gen ELISA | 0.73% (50/6827) | ElISA | 0.73% (50/6827) | RPR |
Frommel D et al. | 1993 | 1991 | Prospective | Volunteer | Addis Ababa | 220 | 133 | 87 | – | 2nd Gen ELISA | – | – | 1.4% (3/220) | ELISA | – | – |
Gelaw B et al. | 2007 | 2002–2003 | Prospective | - | Amhara & Tigrai | 600 | 578 | 22 | – | – | 6.2% (37/600) | Immunochromatography | 1.7% (10/600) | Immunochromatography | – | – |
Gezahegn et al. | 2012 | 2007–2010 | Retrospective | Both | Jimma | 3788 | 3034 | 754 | – | ELISA | 1.0% (39/3788) | – | – | – | – | – |
Hundie GB et al. | 2016 | 2013–2014 | Prospective | Both | National | 56,885 | 40,204 | 16,681 | – | – | 3.9% (2217/56885) | 4th Gen ELISA | 0.52% (294/56885) | – | – | – |
Kebede W et al. | 2017 | 2010–2015 | Retrospective | Both | Jimma | 10,733 | 7608 | 3125 | 0.2%(23/10733) | ELISA | 3.05% (328/10733) | ELISA | 0.2% (22/10733) | ELISA | 0.14% (15/10733) | ELISA |
Yemi A et al. | 2011 | 2010 | Retrospective | Both | Jimma | 6,063 | 4802 | 1261 | 2.1%(129/6063) | ELISA | 2.1% (126/6063) | ELISA | 0.2% (10/6063) | ELISA | 0.7% (44/6063) | RPR |
Tsega E et al. | 1995 | 1992–1994 | Prospective | Volunteer | Addis Ababa | 500 | – | – | – | – | – | – | 1.4% (7/500) | ELISA | – | – |
Tsega E et al. | 1987 | 1986 | Prospective | Volunteer | Addis Ababa | 459 | 409 | 50 | – | – | 11% (50/459 | ELISA | – | – | – | – |
Tessema B et al. | 2010 | 2003–2007 | Retrospective | Both | North Gondar | 6361 | 5592 | 769 | 3.8%(239/6361) | ELISA | 4.7% (298/6361) | ELISA | 0.7% (35/6361) | ELISA | 1.3% (83/6361) | RPR |
Terefe JE et al. | Unpublished | 2008–2013 | Retrospective | Both | Addis Ababa | 173,207 | 135,007 | 38,200 | 1.6%(2848/173207) | ELISA | 5.0% (8743/173207) | ELISA | 1.4% (2357/173207) | ELISA | 0.1% (93/173207) | ELISA |
Sisay Y et al. | 1995 | 1987–1989 | Retrospective | Both | National | 19,408 | 16,735 | 2473 | – | – | – | – | – | – | 4.5% (870/19408) | – |
Birhan W et al. | Unpublished | 2016–2017 | Prospective | Volunteer | Amhara | 987 | 554 | 433 | 0.4%(4/987) | 4th Gen ELISA | 3.65% (36/987) | 4th Gen ELISA | 0.2% (2/987) | ELISA | 0.91% (9/987) | RPR + TPHA |
Ataro Z et al. | 2018 | 2010–2013 | Retrospective | Both | Dire Dawa | 6376 | 5430 | 946 | 1.24%(79/6376) | ELISA | 4.67% (275/6376) | ELISA | 0.96% (61/6376) | ELISA | 0.44% (28/6376) | RPR |
Mohammed Y et al. | 2016 | 2010–2013 | Retrospective | Both | Jijiga | 4224 | 4171 | 53 | 0.1% (6/4224) | ELISA | 10.9% (460/4224) | ELISA | 0.4% (17/4224) | ELISA | 0.1% (4/4224) | ELISA |
Assefa A et al. | 2013 | 2007–2008 | Prospective | Both | Bahir Dar | 2384 | 2177 | 207 | – | – | 4.11% (98/2384) | ELISA | 0.63% (5/2384) | ELISA | – | – |
Biadgo B et al. | 2017 | 2010–2012 | Retrospective | Both | North Gondar | 6741 | 5311 | 1160 | 2.24% (145/6471) | 4th Gen ELISA | 3.6% (233/6471) | 3rd Gen ELISA | 0.8% (51/6471) | 3rd Gen ELISA | – | – |
Berhanselase M | 2016 | 2009–2103 | Retrospective | Both | Hawassa | 6306 | 5471 | 835 | 1.6% (101/6306) | 4th Gen ELISA | 4.8% (303/6306) | ELISA | 0.6% (38/6306) | ELISA | 0.5% (32/6306) | RPR |
Biseteg FS et al. | 2016 | 2015 | Prospective | - | Wolaytsodo | 390 | 291 | 99 | 6.4% (25/390) | 4th Gen ELISA | 9.5% (37/390) | 3rd Gen ELISA | 8.5% (33/390) | 3rd Gen ELISA | 7.9% (31/390) | ELISA |
Bonja F et al. | 2017 | 2015 | Prospective | Both | Hawassa | 384 | 258 | 126 | 1.6% (6/384) | – | 4.2% (16/384) | – | 0.5% (2/384) | – | 0.8% (3/384) |  |
Kassu A et al. | 2006 | 1995–2002 | Retrospective | Both | North Gondar | 11,204 | 10,659 | 545 | 9.9% (1109/11204) | ELISA | – | – | – | – | – | – |
Rahlenbeck SL et al. | 1997 | 1994–1995 | Prospective | Both | North Gondar | 2186 | 2186 | 0 | 14.5% (317/2186) | ELISA | 14.4% (79/549) | 3rd Gen latex test | – | – | 12.9% (283/2186) | RPR |
Zewde D et al. | 1991 | 1989 | Prospective | - | Addis Ababa | 408 | – | – | 2.9% (12/408) | ELISA | 10.8% (44/408) | ELISA | – | – | – | – |
Desie A et al. | 2007 | 2006 | Prospective | Both | Bahir Dar | 324 | 283 | 41 | 11.7% (38/324) | 4th Gen ELISA | 25% (81/324) | 3rd Gen ELISA | 13.3% (43/324) | 3rd Gen ELISA | 1.2% (4/324) | RPR |
Ramos JM et al. | 2008 | 1998–2006 | Retrospective | Both | west Arsi | 3305 | 2754 | 551 | 1.5% (51/3305) | Immunochromatography | – | – | – | – | – | – |
Ramos JM et al. | 2016 | 2007–2012 | Retrospective | – | west Arsi | 2606 | – | – | 0.73% (19/2606) | Immunochromatography | 4.95% (129/2606) | Immunochromatography | 1.68% (44/2606) | Immunochromatography | 0.84% (22/2606) | RPR |
sentlens RE et al. | 2002 | 1991 | Prospective | – | Ethiopia | 2610 | 2069 | 505 | 7.7% (207/2610) | ELISA | – | – | – | – | – | – |
Dro E et al. | 2008 | 2004 | Prospective | – | North Gondar | 600 | 537 | 63 | 4.5% (27/600) | ELISA | 8.2% (49/600) | ELISA | 5.8% (35/600) | ELISA | – | – |
Kabato AA et al. | 2016 | 2015 | Prospective | – | Arba Minch | 359 | 179 | 162 | – | – | 4.7% (17/359) | ELISA | – | – | – | – |
Shiferaw E et al. | 2019 | 2014/2015- 2017/2018 | Retrospective | Both | Bahir Dar | 35,435 | 23,032 | 12,403 | 0.5% (160/35435) | ELISA | 3.9% (1389/35435) | ELISA | 0.6% (203/35435) | ELISA | 1.2% (429/35435) | ELISA |
Azerefegn E et al. | 2018 | 2015 | Retrospective | Both | Hawassa | 6849 | – | – | – | 4th Gen ELISA | – | – | – | – | – | – |
Berhanu S et al. | 2018 | 2017 | Retrospective | Both | Debre tabor | 7255 | – | – | – | 4th Gen ELISA | – | – | – | – | – | – |
Bialfew Y et al. | 2018 | 2018 | Prospective | Volunteer | Debre Markos | 403 | – | – | – | ELISA | – | – | – | – | – | – |
Heyredin I et al. | 2019 | 2018 | Prospective | Both | Dire Dawa | 500 | – | – | – | ELISA | – | – | – | – | – | – |
Assefa A et al. | 1994 | 1989–1993 | Retrospective | – | Gondar | 3696 | 3066 | 630 | 10.85 (401/3696) | ELISA | – | – | – | – | 7.9% (181/2299) | RPR |
Negash M et al. | 2019 | 2018 | Prospective | Volunteer | Debre Tabor | 310 | 198 | 112 | 2.58% (8/310) | ELISA | 5.81% (18/310) | ELISA | 4.2%(13/310) | ELISA | – | – |
Tigabu et l | 2019 | 2018 | Retrospective | Volunteer | Gondar | 5983 | 5118 | 856 | 2.5%(147/5983) | 4th gen ELISA | 4.1%(244/5983) | 3rd gen ELISA | 1.6%(98/5983) | 3rd gen ELISA | – | – |