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Table 2 Serum levels of pro-inflammatory cytokines are elevated in INRs with low CD4+ T cell counts

From: Association between CD4+ T cell counts and gut microbiota and serum cytokines levels in HIV-infected immunological non-responders

Cytokines (pg/mL) CD4 < 200 (N = 17) CD4 > 200 (N = 17) P value
TNF-α 11.14 ± 1.83 9.62 ± 1.65 0.0070*
IP-10 87.54 ± 51.21 53.61 ± 31.60 0.0261*
IL-1α 39.80 ± 6.56 33.91 ± 7.26 0.0141*
MCP-1 163.20 ± 45.38 136.90 ± 42.65 0.1309
D-dimer 1337.00 ± 864.50 1218.00 ± 984.60 0.1705
sCD14 1,737,315 ± 463,779 1,617,557 ± 532,146 0.2208
TNF-β 2.02 ± 0.93 1.76 ± 0.65 0.4279
IL-1β 8.55 ± 1.93 7.94 ± 1.34 0.2313
IL-6 40,486 ± 6550 36,234 ± 7964 0.2451
CRP 2,147,413 ± 2,167,463 4,394,271 ± 3,818,065 0.0834
  1. Data are presented as Mean ± SD unless otherwise indicated. P values were calculated using Mann–Whitney test. Red marked lines represent P < 0.05. TNF-α tumor necrosis factor-alpha, IP-10 interferon gamma-inducible protein 10, IL-1α interleukin 1 alpha, MCP-1 monocyte chemotactic protein-1, sCD14 soluble cluster of differentiation 14, CRP C reactive protein
  2. *P < 0.05