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Table 1 Study cohort characteristics

From: Association between CD4+ T cell counts and gut microbiota and serum cytokines levels in HIV-infected immunological non-responders

  CD4 < 200 (N = 17) CD4 > 200 (N = 17) P value
Mean age (years) 50 ± 9 47 ± 7 0.2619
Weight (kg) 54.71 ± 9.71 58.18 ± 8.63 0.1895
BMI (kg/m2) 21.19 ± 3.52 21.69 ± 2.92 0.4691
Time on ART (years) 7 ± 3 9 ± 2 0.0951
Gender, N (%)
 Male 7 (41.2) 8 (47.1) > 0.9999
 Female 10 (50.0) 9 (52.9)
Ethnicity, N (%)
 Han 4 (23.5) 4 (23.5) > 0.9999
 Other minorities 13 (58.8) 13 (76.5)
Acquisition of HIV, N (%)
 Injection drug use 3 (17.6) 1 (5.9) 0.7309
 Sexual route 12 (70.6) 14 (82.3)
 Unknown 2 (11.8) 2 (11.8)
T cells (cells/μL)
 CD4+ T cell counts before ART 159 ± 143 210 ± 149 0.1425
 CD3+ T cell counts 642 ± 263 764 ± 178 0.0518
 CD4+ T cell counts 149 ± 38 266 ± 57 < 0.0001*
 CD8+ T cell counts 448 ± 233 454 ± 171 0.4902
 CD4/CD8 ratio 0.40 ± 0.20 0.72 ± 0.45 0.0033*
 Nadir CD4+ T cell counts 144 ± 37 239 ± 36 < 0.0001*
ART regimens, N (%)
 NRTI + NNRTI 13 (76.5) 17 (100) 0.1026
 NRTI + PI 4 (23.5) 0 (0)
 3TC + AZT + EFV 4 (23.5) 5 (29.4) 0.1404
 3TC + AZT + NVP 3 (17.6) 6 (35.3)
 3TC + TDF + EFV 5 (29.4) 5 (29.4)
 3TC + AZT + LPV 2 (11.8) 0 (0)
 3TC + TDF + NVP 1 (5.9) 1 (5.9)
 TDF + AZT + LPV 1 (5.9) 0 (0)
 3TC + LPV 1 (5.9) 0 (0)
  1. Data are presented as Mean ± SD unless otherwise indicated. P values were calculated using Mann–Whitney test. Red marked lines represent P < 0.05. BMI body mass index, HIV human immunodeficiency virus, ART antiretroviral therapy, NRTI nucleoside reverse transcriptase inhibitor, NNRTI non-nucleoside reverse transcriptase inhibitor, PI protease inhibitor, 3TC lamivudine, AZT zidovudine, EFV efavurebz, NVP nevirapine, TDF tenofovir, LPV lopinavir
  2. *P < 0.05