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Table 2 Univariable and multivariable analysis of TST and IGRA positivity

From: Tuberculosis infection screening in children with close contact: a hospital-based study

  IGRA positivity (≥ 8 spots) TST(≥ 10 mm)
  n/N (%) p for X2 test# Adjusted OR*(95%CI) n/N (%) p for X2 test# Adjusted OR*(95%CI)
Sex   0.32    0.98  
 Male 35/3748 (0.9%)   Reference 115/3748 (3.1%)   Reference
 Female 17/2454 (0.7%)   0.7 (0.4–1.2) 76/2454 (3.1%)   1.0 (0.8–1.3)
Age(years)   0.006    0.049  
 0–2 y 12/2327 (0.5%)   Reference* 63/2327 (2.7%)   Reference*
 3–4 y 4/924 (0.4%)   0.8 (0.3–2.2)* 21/924 (2.3%)   0.8 (0.5–1.2)
 5–18 36/2951 (1.2%)   2.5 (1.4–4.4)* 107/2951 (3.6%)   1.3 (1.1–1.8)*
District    < 0.001     < 0.001  
 Eastern 28/4662 (0.6%)   Reference* 109/4662 (2.3%)   Reference*
 Middle 10/1042 (1.0%)   2.1 (1.1–3.7)* 44/1042 (4.2%)   2.0 (1.5–2.6)*
 Western 14/498 (2.8%)   3.2 (1.7–6.1)* 38/498 (7.6%)   3.2 (2.4–4.4)*
Resident place   0.78    0.82  
 City 27/3376 (0.8%)   Reference 105/3376 (3.1%)   Reference
 Rural 25/2826 (0.9%)   1.5 (0.9–2.6) 86/2826 (3.0%)   1.0 (0.8–1.3)
BCG vaccination history   0.98    0.07  
 Yes 51/6086 (0.8%)   186/6086 (3.1%)   Reference
 No 1/116 (0.9%)   5/116 (4.3%)   1.2 (0.7–2.1)
Presence of BCG scar   0.79    0.77  
 Yes 49/5895 (0.8%)   Reference 183/5895 (3.1%)   Reference
 No 3/307 (1.0%)   2.0 (0.8–5.0) 8/307 (2.6%)   0.9 (0.5–1.6)
Exposure level    < 0.001     < 0.001  
 No reported contact risk 41/5833 (0.7%)   Reference* 151/5833 (2.6%)   Reference*
 Non-household contact risk 6/274 (2.2%)   1.5 (0.6–3.6)* 23/274 (8.4%)   2.7 (1.9–3.9)*
 Household contact risk 5/95 (5.3%)   6.1 (2.7–13.9)* 17/95 (17.9%)   6.9 (4.5–10.7)*
  1. Data are n/N (%),unless otherwise indicated. n/N (%) is number positive /number with test results (proportion positive)
  2. BCG Bacille Calmette Guerin, IGRA interferon-gamma release assay, TST tuberculin skin test, OR odd ratio, CI confidence interval
  3. #: Univariable analysis; *: multivariable analysis, controlling for variables with p < 0.05 in univariable analysis. p values from the multivariable analysis for IGRA positivity was 0.02,0.005, 0.001 for age, district and exposure level respectively, for TST positivity was 0.13, < 0.001, < 0.001 for age, district and exposure level respectively