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Table 2 Demographics, clinical characteristics and laboratory findings of survivors and non-survivors

From: Clinical characteristics and a decision tree model to predict death outcome in severe COVID-19 patients

Variables

Non-survivor (N = 75)

Survivor (N = 2094)

P valuea

Age, years

72 (67, 82)

61 (50, 69)

 < 0.001

Sex

  

0.003

 Male

49 (65)

987 (47)

 

 Female

26 (35)

1107 (53)

 

Smoking history

  

0.325

 Never

66 (88)

1919 (92)

 

 Former

3 (4)

77 (4)

 

 Current

6 (8)

98 (5)

 

Body temperature

  

 < 0.001

 < 37·3 ℃

54 (72)

1998 (95)

 

 37.3–38.0 ℃

12 (16)

75 (4)

 

 > 38.0 ℃

9 (12)

21 (1)

 

Oxygen saturation

  

 < 0.001

 ≤ 93%

59 (79)

211 (10)

 

 > 93%

16 (21)

1883 (90)

 

Heart rate

  

 < 0.001

 Normal

51 (68)

1759 (84)

 

 Abnormal

24 (32)

335 (16)

 

Respiratory rate

  

 < 0.001

 ≤ 20 per minute

26 (35)

1547 (74)

 

 21–29 per minute

35 (47)

493 (24)

 

 ≥ 30 per minute

14 (19)

54 (3)

 

No. of comorbidities

  

 < 0.001

 0

11 (15)

1024 (49)

 

 1

17 (23)

574 (27)

 

 ≥ 2

47 (63)

496 (24)

 

No. of system symptoms

  

0.03

 0

3 (4)

90 (4)

 

 1

14 (19)

714 (34)

 

 2

49 (65)

1081 (52)

 

 ≥ 3

9 (12)

209 (10)

 

White blood cell count, × 109/L

10.2 (7.27, 14.09)

5.75 (4.71, 6.94)

 < 0.001

Neutrophil count, × 109/L

9.62 (6.8, 13.53)

3.42 (2.59, 4.46)

 < 0.001

Lymphocyte count, × 109/L

0.56 (0.4, 0.8)

1.56 (1.17, 1.92)

 < 0.001

Neutrophil-to-lymphocyte ratio

16.98 (11.88, 26.16)

2.18 (1.6, 3.15)

 < 0.001

Monocyte count, × 109/L

0.38 (0.22, 0.64); n = 75

0.48 (0.38, 0.59); n = 2087

0.002

Eosinophilia count, × 109/L

0.01 (0, 0.04); n = 75

0.11 (0.06, 0.18); n = 2087

 < 0.001

Basophilia count, × 109/L

0.01 (0, 0.02); n = 75

0.03 (0.02, 0.04); n = 2088

 < 0.001

Red blood cell count, × 109/L

4.02 (3.31, 4.34); n = 75

4.02 (3.64, 4.4); n = 2083

0.051

Hemoglobin, g/L

118 (101, 134); n = 75

121 (110, 132); n = 2083

0.213

Platelet count, × 109/L

172 (89, 263); n = 75

223 (182, 273); n = 2089

 < 0.001

C-reactive protein, mg/L

89.33 (38.26, 135.91); n = 75

1.18 (0.5, 6.09); n = 2001

 < 0.001

Lactic dehydrogenase, IU/L

429.14 (366, 541.2); n = 73

175.2 (148.9, 211.2); n = 1989

 < 0.001

Interleukin-6, pg/mL

65.28 (20.41, 154.1); n = 27

2.42 (1.5, 5.91); n = 1338

 < 0.001

Procalcitonin, ng/mL

0.28 (0.14, 0.66); n = 63

0.04 (0.03, 0.08); n = 1398

 < 0.001

D-dimer, μg/mL

2.43 (0.78, 5.61); n = 47

0.37 (0.17, 0.74); n = 1074

 < 0.001

  1. Data are n (%), n/N (%), or median (IQR), unless specified otherwise. Temperature, oxygen saturation, heart rate and respiratory rate were detected at rest when patients were admitted to hospital
  2. ap values indicate differences between survivors and non-survivors
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BMC Infectious Diseases

ISSN: 1471-2334

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