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Table 3 Cytokines values and comparisons among study subgroups

From: Interleukin 6 as a marker of severe bacterial infection in children with sickle cell disease and fever: a case–control study

  Cases (n = 79) Controls (n = 58) p value SBI (n = 4) VI (n = 41) NPI (n = 33) p value
IL-1β pg/ml 33 (1.8–242.5) 29.5 (1.8–212) 0.861 57.9 (1.8–190) 37 (1.8–289) 33 (1.8–166) 0.828
IL-2 pg/ml 6.2 (6.2–6.2) 6.2 (6.2–6.2) 0.565 ND 6.2 (6.2–6.2) 6.2 (6.2–6.2) 0.763
IL-4 pg/ml 2.2 (2.2–85.5) 2.2 (2.2–91) 0.509 14.6 (2.2–149.5) 2.2 (2.2–69) 2.2 (2.2–226) 0.805
IL-6 pg/ml 0.7 (0.7–0.7) ND 0.008 163 (70.4–459.5) 0.7 (0.7–0.7) 0.7 (0.7–0.7)  < 0.001
IL-8 pg/ml 41 (30–74) 36 (30–52) 0.191 49 (32.5–68.5) 44 (30–99) 38 (30–72) 0.919
IL-10 pg/ml 0.9 (0.9–73) 0.9 (0.9–34) 0.218 17.4 (0.9–116.5) 9.9 (0.9–94) 0.9 (0.9–58) 0.561
IL-12p70 pg/ml ND ND ND ND ND
IL-17a pg/ml 4.4 (4.4–266) 44 (4.4–233) 0.828 53.7 (4.4–263.5) 4.4 (4.4–248) 35 (4.4–284) 0.912
TNF-α pg/ml 59.0 (11–112) 50.5 (23–92) 0.674 24.5 (14–52.5) 64 (26–156) 64 (4.9–106) 0.357
IFN-γ pg/ml 41 (0.4–152) 34 (0.4–97) 0.324 0.4 (0.4–20.7) 57 (0.4–203) 41 (0.4–132) 0.201
  1. Variables with significant differences (p value < 0.05) are highlighted in bold font
  2. ND  non-detectable in any of the patients of the subgroup