Table 3 Cytokines values and comparisons among study subgroups
Cases (n = 79) | Controls (n = 58) | p value | SBI (n = 4) | VI (n = 41) | NPI (n = 33) | p value | |
|---|---|---|---|---|---|---|---|
IL-1β pg/ml | 33 (1.8–242.5) | 29.5 (1.8–212) | 0.861 | 57.9 (1.8–190) | 37 (1.8–289) | 33 (1.8–166) | 0.828 |
IL-2 pg/ml | 6.2 (6.2–6.2) | 6.2 (6.2–6.2) | 0.565 | ND | 6.2 (6.2–6.2) | 6.2 (6.2–6.2) | 0.763 |
IL-4 pg/ml | 2.2 (2.2–85.5) | 2.2 (2.2–91) | 0.509 | 14.6 (2.2–149.5) | 2.2 (2.2–69) | 2.2 (2.2–226) | 0.805 |
IL-6 pg/ml | 0.7 (0.7–0.7) | ND | 0.008 | 163 (70.4–459.5) | 0.7 (0.7–0.7) | 0.7 (0.7–0.7) | < 0.001 |
IL-8 pg/ml | 41 (30–74) | 36 (30–52) | 0.191 | 49 (32.5–68.5) | 44 (30–99) | 38 (30–72) | 0.919 |
IL-10 pg/ml | 0.9 (0.9–73) | 0.9 (0.9–34) | 0.218 | 17.4 (0.9–116.5) | 9.9 (0.9–94) | 0.9 (0.9–58) | 0.561 |
IL-12p70 pg/ml | ND | ND | – | ND | ND | ND | – |
IL-17a pg/ml | 4.4 (4.4–266) | 44 (4.4–233) | 0.828 | 53.7 (4.4–263.5) | 4.4 (4.4–248) | 35 (4.4–284) | 0.912 |
TNF-α pg/ml | 59.0 (11–112) | 50.5 (23–92) | 0.674 | 24.5 (14–52.5) | 64 (26–156) | 64 (4.9–106) | 0.357 |
IFN-γ pg/ml | 41 (0.4–152) | 34 (0.4–97) | 0.324 | 0.4 (0.4–20.7) | 57 (0.4–203) | 41 (0.4–132) | 0.201 |