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Table 1 Baseline characteristics of patients

From: Interleukin 6 as a marker of severe bacterial infection in children with sickle cell disease and fever: a case–control study

  Cases
(n = 79)
Controls (n = 58) p value
Age in years [m (IQR)] 4.1 (1.7–7.5) 5.2 (2.1–9.3) 0.193
Male [no. (%)] 62 (78.5) 36 (62.1) 0.035
Genotype [no. (%)]    
 SS 68 (86.1) 52 (89.7) 0.592
 SC 5 (6.3) 4 (6.9)  
 Sβ-thalassemia 6 (7.6) 2 (3.4)  
Newborn screening [no. (%)] 72 (91.1) 47 (81) 0.084
Parents’ origin [no. (%)]    
 Africa 33 (41.8) 42 (72.4) 0.001
 America 45 (57) 14 (24.1)  
 Other 1 (1.3) 2 (3.4)  
Complete vaccination status [no. (%)] 70 (88.6) 48 (85.7) 0.618
Penicillin prophylaxis [no. (%)] 76 (98.7) 53 (91.4) 0.084
Hydroxyurea [no. (%)] 39 (49.4) 33 (56.9) 0.132
Vitamin D supplementation [no. (%)] 77 (97.5) 56 (96.6) 0.753
Splenectomy [no. (%)] 8 (10.1) 4 (6.9) 0.509
Central venous catheter [no. (%)] 18 (22.8) 4 (6.9) 0.012
Hypertransfusional regimen [no. (%)] 9 (11.4) 2 (3.4) 0.117
No. of previous hospital admissions [m (IQR)] 6 (2–10.5) 5 (2–9) 0.138
  1. m (IQR) = median (interquartile range). No. = number
  2. Variables with significant differences (p value < 0.05) are highlighted in bold font