Table 2 Initial diagnosis; delay between first diagnosis and final diagnosis of co-infection; therapeutic intervention; outcomes and follow-up of COVID-19/dengue cases
From: SARS-CoV-2/DENV co-infection: a series of cases from the Federal District, Midwestern Brazil
Case | Sex | Initial diagnosis | Delay | Therapeutic intervention | Outcome and follow-up |
|---|---|---|---|---|---|
1 | M | Dengue fever | 10 days | Analgesics | Clinical improvement in 10 days |
2 | F | Dengue fever | 2 days | Analgesics Hydration with 0.9% saline Amoxicillin Clavulanate Prophylaxis of thrombosis with compression stockings | 7 days in hospital; no follow-up |
3 | F | COVID-19/dengue | None | Analgesics Enoxaparin 40 mg/day | 4 days in hospital; no follow-up |
4 | M | Dengue fever | 5 days | Analgesics Prednisone dose was increased from 5 to 15 mg for 5 days, to avoid adrenal insufficiency | Clinical improvement in 15 days |
5 | F | Dengue fever | 3 days | Hydroxychloroquine 400 mg 2x/day for 1 day Chloroquine 450 mg for 1 day Enoxaparin 40 mg/day for 2 weeks Azithromycin 500 mg/day for 5 days Ceftriaxone 2 g/day for 5 days | 2 hospitalizations (due to dengue symptoms, and later, due to childbirth) Clinical improvement in 13 days |
6 | M | COVID-19/dengue | None | Self-medication with ivermectin (6 mg/kg) | Clinical improvement in 4 days |
7 | M | COVID-19/dengue | None | Analgesics Hydration with 0.9% saline | Clinical improvement in 14 days |
8 | F | COVID-19 | 6 days | Azithromycin (500 mg) for 2 days Self-medication with ivermectin (6 mg/kg) | – |
9 | M | COVID-19/dengue | None | Analgesics | Clinical improvement in 4 days |
10 | F | COVID-19/dengue | None | Analgesics Prednisone 20 mg for 5 days Hydration with 0.9% saline | Clinical improvement in 21 days |
11 | F | Dengue fever | 7 days | Azithromycin (500 mg) for 5 days Prednisone dosage increased from 5 to 20 mg for 7 days | Pulmonary resolution in 15 days (patient had 30% of lung commitment) |
12 | M | COVID-19/dengue | None | None | Clinical improvement in 7 days |
13 | F | Dengue fever | 12 days | Corticoids, azithromycin (500 mg) Oxygen in the first 2 days | 5 days in hospital; clinical improvement in 20 days |