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Table 3 Comparison of CLEC4E SNPs polymorphisms in relation to TB risk in Chinese Han population stratified by sex

From: A case-control study on correlation between the single nucleotide polymorphism of CLEC4E and the susceptibility to tuberculosis among Han people in Western China

SNP/Sex

Allele

Case n(%)

Control n(%)

OR (95% CI) a

P*

Pa

P***

Genotype

Case n(%)

Control n(%)

P*

P***

rs10841856/Male

G

517(47.69)

652(40.61)

1.334(1.142,1.560)

<0.001

<0.001

0.001

GG

114(21.03)

134(16.32)

<0.001

<0.001

A > G

A

567(52.31)

974(59.39)

    

AG

289(53.32)

400(48.72)

0.002

0.008

        

AA

139(25.65)

287(34.96)

  

rs10841856/Female

G

297(41.48)

606(43.06)

0.944(0.785,1.134)

0.486

0.537

1.000

GG

62(17.32)

132(18.51)

0.509

1.000

A > G

A

419(58.52)

769(56.94)

    

AG

173(48.32)

350(49.09)

0.608

1.000

        

AA

123(34.36)

231(32.40)

  

rs10770847/Male

G

355(32.75)

471(28.75)

1.188(1.005,1.405)

0.027

0.044

0.106

GG

54(9.96)

57(6.96)

0.024

0.096

A > G

A

729(67.25)

1167(71.25)

    

AG

247(45.57)

357(43.59)

0.194

0.776

        

AA

241(44.46)

405(49.45)

  

rs10770847/Female

G

203(28.43)

417(29.28)

0.973(0.795,1.189)

0.682

0.787

1.000

GG

28(7.84)

68(9.55)

0.416

1.000

A > G

A

511(71.57)

1007(70.72)

    

AG

147(41.18)

281(39.47)

0.756

1.000

        

AA

182(50.98)

363(50.98)

  

rs1077855 /Male

A

466(43.07)

686(41.83)

1.048(0.896,1.226)

0.522

0.556

1.000

AA

96(17.74)

134(16.34)

0.389

1.000

G > A

G

616(56.93)

954(58.17)

    

AG

274(50.65)

418(50.98)

0.616

1.000

        

GG

171(31.61)

268(32.68)

  

rs1077855 /Female

A

317(44.27)

600(42.31)

1.091(0.908,1.311)

0.387

0.352

1.000

AA

70(19.55)

126(17.77)

0.484

1.000

G > A

G

399(55.73)

818(57.69)

    

AG

177(49.44)

348(49.08)

0.829

q.000

        

GG

111(31.61)

235(33.15)

  

rs4480590/ Male

A

269(24.86)

429(26.25)

0.911(0.762,1.089)

0.416

0.307

1.000

AA

35(6.47)

50(6.12)

0.996

1.000

G > A

G

813(75.14)

1205(73.75)

    

AG

199(36.78)

329(40.27)

0.206

1.000

        

GG

307(56.75)

438(53.61)

  

rs4480590 /Female

A

178(24.93)

344(24.23)

1.089(0.881,1.346)

0.729

0.430

1.000

AA

25(7.00)

41(5.77)

0.464

1.000

G > A

G

536(75.07)

1076(75.77)

    

AG

128(35.85)

262(36.90)

0.852

1.000

        

GG

204(57.14)

407(57.32)

  
  1. P *was calculated by the Chi-square test. P** and OR (95% CI) a was adjusted by age. P*** was calculated after Bonferroni correction. SNP = single-nucleotide polymorphism; OR = odds ratio; CI = confidence interval
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BMC Infectious Diseases

ISSN: 1471-2334

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