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Table 3 Meta-analysis of virulence factors for UPEC isolates from urinary tract infections

From: Virulence factors and antimicrobial resistance of uropathogenic Escherichia coli (UPEC) isolated from urinary tract infections: a systematic review and meta-analysis

Antibiotics No of studies n/N Random model Heterogeneity Egger’s test
% (95% CI) P Q P I2 t P
aer 3 229/437 52.4 (0.48–0.57) 0.315 189.2 < 0.001 93.1 4.45 0.001
afa 5 98/701 14.0 (0.12–0.17) < 0.001 169.6 < 0.001 92.3 4.54 0.001
chuA 1 46/227 20.3 (0.16–0.26) < 0.001 93.10 < 0.001 86.0 25.9 < 0.001
cnf1 5 91/682 13.3 (0.11–0.16) < 0.001 71.34 < 0.001 81.8 13.2 < 0.001
Colicin 1 13/137 9.5 (0.06–0.16) < 0.001 45.42 < 0.001 71.4 16.9 < 0.001
CSH 1 120/150 80.0 (0.73–0.86) < 0.001 242.1 < 0.001 94.6 39.3 < 0.001
eco274 1 99/227 43.6 (0.37–0.50) 0.055 157.9 < 0.001 91.8 33.7 < 0.001
fimH/MSHA 10 881/1170 75.3 (0.73–0.78) < 0.001 210.7 < 0.001 93.8 0.72 0.489
fimP/MRHA 4 219/616 35.6 (0.32–0.39) < 0.001 152.0 < 0.001 91.5 8.02 < 0.001
fyuA 1 41/227 18.1 (0.14–0.24) < 0.001 85.68 < 0.001 84.8 24.8 < 0.001
hlyA 12 334/1511 22.1 (0.20–0.24) < 0.001 241.9 < 0.001 94.6 2.62 0.022
iucD 2 130/198 65.7 (0.59–0.72) < 0.001 203.3 < 0.001 93.6 29.9 < 0.001
iutA 2 144/233 61.8 (0.55–0.68) < 0.001 198.6 < 0.001 93.5 18.9 < 0.001
kpsMTII 2 120/198 60.6 (0.54–0.67) 0.003 191.2 < 0.001 93.2 36.4 < 0.001
PAI 3 265/480 55.2 (0.51–0.60) 0.023 241.8 < 0.001 94.6 3.80 0.003
pap 9 350/1158 30.2 (0.28–0.33) < 0.001 87.35 < 0.001 98.9 0.54 < 0.001
sat 1 28/107 26.2 (0.19–0.35) < 0.001 100.3 < 0.001 87.0 25.3 < 0.001
sfa 5 262/701 37.4 (0.34–0.41) < 0.001 10.08 < 0.001 90.8 0.05 0.001
shiA 1 209/227 92.1 (0.88–0.95) < 0.001 292.1 < 0.001 95.6 45.4 < 0.001
sisA 1 164/227 72.2 (0.66–0.78) < 0.001 234.0 < 0.001 94.5 40.9 < 0.001
sisB 1 56/227 24.7 (0.19–0.31) < 0.001 106.9 < 0.001 89.8 27.8 < 0.001
sivH 1 81/227 35.7 (0.30–0.42) < 0.001 137.5 < 0.001 90.6 31.5 < 0.001
traT 2 266/354 75.1 (0.70–0.79) < 0.001 236.2 < 0.001 94.5 40.7 < 0.001
vat 1 63/227 27.8 (0.22–0.34) < 0.001 115.9 < 0.001 88.8 28.9 < 0.001
yfcv 1 57/227 25.1 (0.20–0.31) < 0.001 108.2 < 0.001 88.0 27.9 < 0.001