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Table 3 Meta-analysis of virulence factors for UPEC isolates from urinary tract infections

From: Virulence factors and antimicrobial resistance of uropathogenic Escherichia coli (UPEC) isolated from urinary tract infections: a systematic review and meta-analysis

Antibiotics

No of studies

n/N

Random model

Heterogeneity

Egger’s test

% (95% CI)

P

Q

P

I2

t

P

aer

3

229/437

52.4 (0.48–0.57)

0.315

189.2

< 0.001

93.1

4.45

0.001

afa

5

98/701

14.0 (0.12–0.17)

< 0.001

169.6

< 0.001

92.3

4.54

0.001

chuA

1

46/227

20.3 (0.16–0.26)

< 0.001

93.10

< 0.001

86.0

25.9

< 0.001

cnf1

5

91/682

13.3 (0.11–0.16)

< 0.001

71.34

< 0.001

81.8

13.2

< 0.001

Colicin

1

13/137

9.5 (0.06–0.16)

< 0.001

45.42

< 0.001

71.4

16.9

< 0.001

CSH

1

120/150

80.0 (0.73–0.86)

< 0.001

242.1

< 0.001

94.6

39.3

< 0.001

eco274

1

99/227

43.6 (0.37–0.50)

0.055

157.9

< 0.001

91.8

33.7

< 0.001

fimH/MSHA

10

881/1170

75.3 (0.73–0.78)

< 0.001

210.7

< 0.001

93.8

0.72

0.489

fimP/MRHA

4

219/616

35.6 (0.32–0.39)

< 0.001

152.0

< 0.001

91.5

8.02

< 0.001

fyuA

1

41/227

18.1 (0.14–0.24)

< 0.001

85.68

< 0.001

84.8

24.8

< 0.001

hlyA

12

334/1511

22.1 (0.20–0.24)

< 0.001

241.9

< 0.001

94.6

2.62

0.022

iucD

2

130/198

65.7 (0.59–0.72)

< 0.001

203.3

< 0.001

93.6

29.9

< 0.001

iutA

2

144/233

61.8 (0.55–0.68)

< 0.001

198.6

< 0.001

93.5

18.9

< 0.001

kpsMTII

2

120/198

60.6 (0.54–0.67)

0.003

191.2

< 0.001

93.2

36.4

< 0.001

PAI

3

265/480

55.2 (0.51–0.60)

0.023

241.8

< 0.001

94.6

3.80

0.003

pap

9

350/1158

30.2 (0.28–0.33)

< 0.001

87.35

< 0.001

98.9

0.54

< 0.001

sat

1

28/107

26.2 (0.19–0.35)

< 0.001

100.3

< 0.001

87.0

25.3

< 0.001

sfa

5

262/701

37.4 (0.34–0.41)

< 0.001

10.08

< 0.001

90.8

0.05

0.001

shiA

1

209/227

92.1 (0.88–0.95)

< 0.001

292.1

< 0.001

95.6

45.4

< 0.001

sisA

1

164/227

72.2 (0.66–0.78)

< 0.001

234.0

< 0.001

94.5

40.9

< 0.001

sisB

1

56/227

24.7 (0.19–0.31)

< 0.001

106.9

< 0.001

89.8

27.8

< 0.001

sivH

1

81/227

35.7 (0.30–0.42)

< 0.001

137.5

< 0.001

90.6

31.5

< 0.001

traT

2

266/354

75.1 (0.70–0.79)

< 0.001

236.2

< 0.001

94.5

40.7

< 0.001

vat

1

63/227

27.8 (0.22–0.34)

< 0.001

115.9

< 0.001

88.8

28.9

< 0.001

yfcv

1

57/227

25.1 (0.20–0.31)

< 0.001

108.2

< 0.001

88.0

27.9

< 0.001