Antibiotics | No of studies | n/N | Random model | Heterogeneity | Egger’s test | ||||
---|---|---|---|---|---|---|---|---|---|
% (95% CI) | P | Q | P | I2 | t | P | |||
Amikacin | 8 | 214/1074 | 19.9 (0.18–0.22) | < 0.001 | 344.4 | < 0.001 | 96.5 | 3.98 | 0.002 |
Amoxicillin | 3 | 322/443 | 72.7 (0.68–0.77) | < 0.001 | 225.6 | < 0.001 | 94.7 | 4.76 | 0.001 |
Amoxiclav | 6 | 407/998 | 40.8 (0.38–0.44) | < 0.001 | 406.2 | < 0.001 | 97.1 | 2.35 | 0.039 |
Ampicillin | 8 | 835/1114 | 75.0 (0.72–0.77) | < 0.001 | 222.9 | < 0.001 | 94.6 | 1.15 | 0.276 |
Ampicillin-sulbactam | 3 | 161/354 | 45.5 (0.40–0.51) | 0.089 | 178.0 | < 0.001 | 93.3 | 5.54 | < 0.001 |
Aztreonam | 2 | 78/354 | 22.0 (0.18–0.27) | < 0.001 | 172.8 | < 0.001 | 93.1 | 24.1 | < 0.001 |
Cefepime | 7 | 280/952 | 29.4 (0.27–0.32) | < 0.001 | 143.3 | < 0.001 | 91.6 | 3.38 | 0.006 |
Cefixime | 3 | 120/443 | 27.1 (0.23–0.31) | < 0.001 | 124.0 | < 0.001 | 90.3 | 5.58 | 0.001 |
Cefoperazone-sulbactam | 2 | 36/198 | 18.2 (0.13–0.24) | < 0.001 | 81.21 | < 0.001 | 85.2 | 24.2 | < 0.001 |
Cefotaxime | 7 | 379/1055 | 35.9 (0.33–0.39) | < 0.001 | 235.5 | < 0.001 | 94.9 | 3.99 | 0.002 |
Cefoxitin | 4 | 104/707 | 14.7 (0.12–0.18) | < 0.001 | 91.61 | < 0.001 | 86.9 | 13.6 | < 0.001 |
Cefpodoxime | 2 | 166/287 | 57.8 (0.52–0.63) | 0.008 | 182.7 | < 0.001 | 93.4 | 11.5 | < 0.001 |
Ceftazidime | 9 | 509/1209 | 42.1 (0.39–0.45) | < 0.001 | 212.1 | < 0.001 | 94.3 | 3.33 | 0.007 |
Ceftriaxone | 5 | 247/844 | 29.3 (0.26–0.32) | < 0.001 | 239.6 | < 0.001 | 95.0 | 5.50 | < 0.001 |
Cefuroxime | 5 | 389/705 | 55.2 (0.51–0.59) | 0.006 | 288.2 | < 0.001 | 95.8 | 3.16 | 0.009 |
Cephalexin | 3 | 146/258 | 56.6 (0.50–0.63) | 0.035 | 189.3 | < 0.001 | 93.7 | 12.8 | < 0.001 |
Cephalothin | 3 | 82/437 | 18.8 (0.15–0.23) | < 0.001 | 181.0 | < 0.001 | 93.4 | 3.23 | 0.008 |
Cephazolin | 3 | 142/258 | 55.0 (0.49–0.61) | 0.106 | 168.4 | < 0.001 | 92.9 | 13.7 | < 0.001 |
Ciprofloxacin | 12 | 792/1781 | 44.5 (0.42–0.47) | < 0.001 | 265.5 | < 0.001 | 95.5 | 0.54 | 0.602 |
Ertapenem | 1 | 1/227 | 0.4 (0.00–0.03) | < 0.001 | 0.799 | 1.000 | 0.00 | 0.49 | 0.634 |
Fosfomycin | 1 | 9/107 | 8.4 (0.04–0.15) | < 0.001 | 37.35 | < 0.001 | 67.9 | 21.0 | < 0.001 |
Gentamicin | 13 | 637/1888 | 33.7 (0.32–0.36) | < 0.001 | 269.6 | < 0.001 | 95.6 | 0.70 | 0.497 |
Imipenem | 7 | 5/767 | 0.7 (0.00–0.02) | < 0.001 | 3.719 | 0.988 | 0.00 | 5.02 | < 0.001 |
Meropenem | 3 | 1/354 | 0.3 (0.00–0.02) | < 0.001 | 1.416 | 1.000 | 0.00 | 2.40 | 0.035 |
Nalidixic acid | 9 | 777/1317 | 59.0 (0.56–0.62) | < 0.001 | 248.2 | < 0.001 | 95.2 | 1.70 | 0.118 |
Nitrofurantoin | 10 | 297/1486 | 20.0 (0.18–0.22) | < 0.001 | 297.1 | < 0.001 | 96.0 | 3.77 | 0.003 |
Norfloxacin | 5 | 286/614 | 46.6 (0.43–0.51) | 0.090 | 273.1 | < 0.001 | 95.6 | 3.20 | 0.009 |
Ofloxacin | 2 | 101/244 | 41.4 (0.35–0.48) | 0.007 | 153.5 | < 0.001 | 92.2 | 13.6 | < 0.001 |
Tetracycline | 6 | 498/721 | 69.1 (0.66–0.72) | < 0.001 | 207.3 | < 0.001 | 94.2 | 2.44 | 0.033 |
Tobramycin | 1 | 30/107 | 28.0 (0.20–0.37) | < 0.001 | 103.8 | < 0.001 | 88.4 | 35.2 | < 0.001 |
Co-trimoxazole | 13 | 1119/1888 | 59.3 (0.57–0.61) | < 0.001 | 177.1 | < 0.001 | 93.2 | 1.06 | 0.313 |