|
Demographic characteristics
|
|
Age (years, IQR)
|
43(34,52)
|
54(44.8,65)
|
< 0.0001
|
|
Male sex, n (%)
|
263 (80.2%)
|
40 (69.0%)
|
0.055
|
|
Comorbidity and Complications
|
|
Cerebral infarction, n (%)
|
14 (4.3%)
|
5 (8.6%)
|
0.182#
|
|
Liver cirrhosis, n (%)
|
5 (1.5%)
|
2 (3.4%)
|
0.284#
|
|
Diabetes, n (%)
|
17 (5.2%)
|
5 (8.6%)
|
0.351#
|
|
Tuberculosis, n (%)
|
47 (14.3%)
|
12 (20.7%)
|
0.215
|
|
Pneumocystis pneumonia, n (%)
|
30 (9.1%)
|
6 (10.3%)
|
0.772
|
|
Bacterial pneumonia, n (%)
|
48 (14.6%)
|
13 (22.4%)
|
0.134
|
|
Cytomegalovirus infection
|
34 (10.4%)
|
7 (12.1%)
|
0.698
|
|
Clinical characteristic
|
|
Time from symptom onset to hospital admission (month, IQR)
|
0.7(0.3,1.0)
|
1(0.3,2.0)
|
0.287
|
|
Maximum body temperature (°C, IQR)
|
37.8 (36.7,39.0)
|
36.6 (36.7,38.3)
|
0.213
|
|
Stiff neck, n (%)
|
24 (7.3%)
|
17 (29.3%)
|
< 0.0001
|
|
Impaired consciousness, n (%)
|
28 (8.5%)
|
22 (37.9%)
|
< 0.0001
|
|
Headache, n (%)
|
243 (74.1%)
|
45(77.6%)
|
0.572
|
|
Seizures, n (%)
|
25 (7.6%)
|
7 (12.1%)
|
0.298#
|
|
Weight loss, n (%)
|
125 (38.1%)
|
29 (50.0%)
|
0.088
|
|
Laboratory data
|
|
CSF glucose (mmol/L, IQR)
|
2.54 (1.9,3.2)
|
2.25 (1.2,3.1)
|
0.045
|
|
Neutrophil count (109/L, IQR)
|
3.4 (2.3,5.4)
|
3.8 (2.1,6.3)
|
0.419
|
|
TBIL (μmol/L, IQR)
|
9.2 (7.0,13.6)
|
13.5 (9.0,19.7)
|
< 0.0001
|
|
HGB (g/L, IQR)
|
115.0 (98.0,130.0)
|
108.0 (94.3126.0)
|
0.235
|
|
PLT (× 106 /L, IQR)
|
186 (126.0,248.8)
|
120 (82,202)
|
< 0.0001
|
|
Urea (mmol/L, IQR)
|
3.8 (3.0,5.5)
|
4.9 (3.7,6.8)
|
0.001
|
|
Creatinine (μmol/L, IQR)
|
59.1 (49.0,71.2)
|
60.3 (49.1,75.6)
|
0.787
|
|
White blood cell count (109/L, IQR)
|
4.6 (3.4,6.5)
|
4.7(3.1,7.2)
|
0.939
|
|
CD4+ T-cell count (cells/μL, IQR)
|
32.0 (13.0,77.3)
|
29.0 (12.8,48.0)
|
0.095
|
|
HIV RNA (log10 copies/mL, IQR)
|
5.1 (3.9,5.7)
|
5.4 (4.9,5.9)
|
0.009
|
|
ICP (mm H2O, IQR)
|
215.0 (160.0,328.0)
|
360.0 (247.0,400.0)
|
< 0.0001
|
|
ART at hospital admission, n (%)
|
198 (51.3%)
|
27(46.6%)
|
0.500
|
