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Table 2 Putative nosocomial transmission clusters

From: Genomic surveillance of antimicrobial resistant bacterial colonisation and infection in intensive care patients

#

Organism

Cluster size (n pt)

Pairwise SNVs

Days between pt. stays

Episodes attributed to transmission (n total (n very likely)) c

Genomic a

Genomic + epi b

1

E. coli ST48

2

2

4

8

1 (0)

2

E. coli ST69

2

2

1

0

1 (1)

3

E. coli ST176

3

2

1–8

0–31

1 (1)

4

E. coli ST354

2

2

0

6

1 (0)

5

K. pneumoniae ST231

2

2

0–2

0

1 (1)

6

K. oxytoca ST340

2

2

0

0

1 (1)

7

E. faecium ST17

2

2

1

11

1 (0)

8

E. faecium ST17

7

7

0–2

0

6 (6)

9

E. faecium ST796

2

2

1

1

1 (0)

10

E. faecium ST796

3

0

1–2

20–62

0 (0)

  1. Pt, patient; SNVs, single nucleotide variants
  2. aPatient cluster identified by genomic analysis; ≤ 20 single nucleotide variants between isolates (Gram-negative species), or ≤ 3 single nucleotide variants between isolates (E. faecium)
  3. bPatient cluster identified by genomic analysis (as defined above) and supported by epidemiological data (≤ 14 days between patient ICU stays or overlapping stays)
  4. cNumber of colonisation and infection episodes likely or very likely attributed to transmission; likely, patient was part of the genomic cluster (as defined above) with ≤14 days between the patient ICU stay and that of another patient in the genomic cluster; very likely, patient was part of the genomic cluster (as defined above) and ICU stay overlapped with ≥1 other patient in the genomic cluster