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Table 2 Putative nosocomial transmission clusters

From: Genomic surveillance of antimicrobial resistant bacterial colonisation and infection in intensive care patients

# Organism Cluster size (n pt) Pairwise SNVs Days between pt. stays Episodes attributed to transmission (n total (n very likely)) c
Genomic a Genomic + epi b
1 E. coli ST48 2 2 4 8 1 (0)
2 E. coli ST69 2 2 1 0 1 (1)
3 E. coli ST176 3 2 1–8 0–31 1 (1)
4 E. coli ST354 2 2 0 6 1 (0)
5 K. pneumoniae ST231 2 2 0–2 0 1 (1)
6 K. oxytoca ST340 2 2 0 0 1 (1)
7 E. faecium ST17 2 2 1 11 1 (0)
8 E. faecium ST17 7 7 0–2 0 6 (6)
9 E. faecium ST796 2 2 1 1 1 (0)
10 E. faecium ST796 3 0 1–2 20–62 0 (0)
  1. Pt, patient; SNVs, single nucleotide variants
  2. aPatient cluster identified by genomic analysis; ≤ 20 single nucleotide variants between isolates (Gram-negative species), or ≤ 3 single nucleotide variants between isolates (E. faecium)
  3. bPatient cluster identified by genomic analysis (as defined above) and supported by epidemiological data (≤ 14 days between patient ICU stays or overlapping stays)
  4. cNumber of colonisation and infection episodes likely or very likely attributed to transmission; likely, patient was part of the genomic cluster (as defined above) with ≤14 days between the patient ICU stay and that of another patient in the genomic cluster; very likely, patient was part of the genomic cluster (as defined above) and ICU stay overlapped with ≥1 other patient in the genomic cluster