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Table 2 Comparison and single logistic analysis for Characteristics of VAP and Non-VAP patients

From: The effect of ventilator-associated pneumonia on the prognosis of intensive care unit patients within 90 days and 180 days

Characteristic All patients (n = 8163) Non-VAP Patients
(n = 7626)
VAP Patients
(n = 537)
Statistical magnitude P OR (95%CI) Logit-P
Age, Mean ± SD 64.06 ± 16.28 64.19 ± 16.22 62.29 ± 16.98 t = 2.620 0.009 0.993 (0.988–0.998) 0.009
Gender, n(%)     χ2 = 0.132 0.716   
 Female 3223 (39.48) 3007 (39.43) 216 (40.22)    Ref  
 Male 4940 (60.52) 4619 (60.57) 321 (59.78)    0.967 (0.809–1.156) 0.716
Ethnicity, n(%)     χ2 = 15.423 0.004   
 White 5902 (72.30) 5543 (72.69) 359 (66.85)    Ref  
 Asian 215 (2.63) 197 (2.58) 18 (3.35)    1.411 (0.861–2.313) 0.172
 Black 563 (6.90) 515 (6.75) 48 (8.94)    1.439 (1.051–1.971) 0.023
 Hispanic/latino 298 (3.65) 285 (3.74) 13 (2.42)    0.704 (0.400–1.240) 0.225
 Other 1185 (14.52) 1086 (14.24) 99 (18.44)    1.408 (1.116–1.775) 0.004
COPD, n(%) 861 (10.55) 794 (10.41) 67 (12.48) χ2 = 2.267 0.132 1.227 (0.940–1.601) 0.133
Heart failure, n(%) 2107 (25.81) 1935 (25.37) 172 (32.03) χ2 = 11.607 < 0.001 1.386 (1.148–1.674) < 0.001
Diabetes, n(%) 2027 (24.83) 1887 (24.74) 140 (26.07) χ2 = 0.473 0.492 1.073 (0.878–1.309) 0.492
Septicemia, n(%) 1493 (18.29) 1324 (17.36) 169 (31.47) χ2 = 66.828 < 0.001 2.186 (1.805–2.647) < 0.001
SAPSII score, M(Q1,Q3) 38.00 (30.00,49.00) 38.00 (30.00,49.00) 41.00 (31.00,52.00) Z = 3.679 < 0.001 1.009 (1.003–1.014) 0.002
SOFA score, Mean ± SD 7.128 ± 3.581 7.096 ± 3.579 7.581 ± 3.585 t = −3.040 0.002 1.037 (1.013–1.062) 0.002
Serum Lactate, M(Q1,Q3) 1.60 (1.10,2.60) 1.60 (1.10,2.60) 1.80 (1.20,3.00) Z = 2.773 0.006 1.051 (1.011–1.092) 0.013
WBC, M(Q1,Q3) 11.60 (8.20,15.70) 11.50 (8.10,15.70) 12.00 (8.70,16.20) Z = 2.068 0.039 1.010 (1.001–1.018) 0.022
INR, M(Q1,Q3) 1.30 (1.10,1.50) 1.30 (1.10,1.50) 1.20 (1.10,1.60) Z = -1.295 0.195 1.067 (0.998–1.141) 0.059
Length of ICU stay, M(Q1,Q3) 3.17 (1.61,6.98) 2.99 (1.48,6.06) 12.69 (7.69,20.81) Z = 27.865 < 0.001 1.140 (1.128–1.152) < 0.001
Length of hospital stay, M(Q1,Q3) 8.52 (5.14,14.65) 8.09 (5.00,13.48) 18.79 (12.33,26.91) Z = 21.875 < 0.001 1.046 (1.040–1.052) < 0.001
Length of ventilation, M(Q1,Q3) 23.50 (8.63,87.33) 20.86 (7.85,69.67) 216.47 (114.57,351.26) Z = 27.780 < 0.001 1.008 (1.007–1.008) < 0.001
Antibiotic treatment, n(%)     Z = 18.883 < 0.001   
 None 1266 (15.51) 1248 (16.37) 18 (3.35)    Ref  
 Single antibiotic 2623 (32.13) 2610 (34.23) 13 (2.42)    0.346 (0.169–0.707) 0.004
 Combined antibiotics 4274 (52.36) 3768 (49.41) 506 (94.23)    9.311 (5.793–14.963) < 0.001
Pathogens species, n(%)
 A.baumannii 6 (0.07) 5 (0.07) 1 (0.19) 0.335 2.850 (0.333–24.400) 0.339
 P.aeruginosa 67 (0.82) 53 (0.69) 14 (2.61) < 0.001 3.825 (2.108–6.939) < 0.001
 MRSA 181 (2.22) 156 (2.05) 25 (4.66) χ2 = 15.760 < 0.001 2.339 (1.519–3.602) < 0.001
 K.pneumoniae 61 (0.75) 54 (0.71) 7 (1.30) 0.120 1.852 (0.839–4.090) 0.127
 MSSA 123 (1.51) 113 (1.48) 10 (1.86) χ2 = 0.489 0.484 1.262 (0.657–2.423) 0.485
E. coli 128 (1.57) 118 (1.55) 10 (1.86) χ2 = 0.322 0.570 1.207 (0.629–2.316) 0.571
 Other pathogens 770 (9.43) 690 (9.05) 80 (14.90) χ2 = 20.094 < 0.001 1.760 (1.370–2.260) < 0.001
90-day mortality, n(%) 2009 (24.61) 1830 (24.00) 179 (33.33) χ2 = 23.569 < 0.001 1.584 (1.314–1.909) < 0.001
180-day mortality, n(%) 2171 (26.60) 1969 (25.82) 202 (37.62) χ2 = 35.762 < 0.001 1.732 (1.444–2.078) < 0.001
  1. RDW red cell distribution width, COPD chronic obstructive pulmonary disease, SOFA septicemia and heart failure, sequential organ failure assessment, WBC white blood cell, A.baumannii Acinetobacter baumannii, P.aeruginosa Pseudomonas aeruginosa, MRSA methicillin-resistant Staphylococcus aureus K.pneumoniae Klebsiella pneumonia, MSSA methicillin-sensitive Staphylo coccus aureus, E. coli Escherichia coli, SAPSII simplified acute physiology score II