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Table 3 Analysis of factors likely to influence 30-day all-cause mortality

From: The impact of infectious diseases consultation on the management and outcomes of Pseudomonas aeruginosa bacteraemia in adults: a retrospective cohort study

Variables

Mortality n/Total (%)

Unadjusted OR (95% CI)

P value

Adjusteda OR (95% CI)

P value

IDC

 Yes

10/91 (11.0)

    

 No

21/37 (56.8)

10.63(4.20–26.89)

< 0.001

7.84 (2.95–20.86)

< 0.001

Age (years)

 < 65

10/53 (18.9)

    

 ≥ 65

21/75 (28.0)

1.67 (0.71–3.94)

0.239

0.69 (0.19–2.44)

0.562

Age (years)

 < 75

15/86 (17.4)

    

 ≥ 75

16/42 (38.1)

2.91 (1.26–6.74)

0.012

1.56 (0.50–4.87)

0.441

Gender

 Female

13/59 (22.0)

    

 Male

18/69 (26.1)

1.25 (0.55–2.84)

0.595

1.54 (0.56–4.28)

0.407

Charlson comorbidity index

 Score < 5

5/50 (10.0)

    

 Score ≥ 5

26/78 (33.3)

4.50 (1.59–12.75)

0.005

5.14 (1.22–21.58)

0.025

Appropriate antibiotic therapy

 Yes

17/88 (19.3)

    

 No

14/40 (35.0)

0.44 (0.19–1.03)

0.059

0.38 (0.06–2.26)

0.289

Surgical intervention for source control

2/21 (9.5)

    

29/107 (27.1)

3.53 (0.77–16.22)

0.105

2.64 (0.44–15.77)

0.287

Febrile neutropenia

 No

22/83 (26.5)

    

 Yes

9/45 (20.0)

0.69 (0.29–1.67)

0.415

0.97 (0.33–2.89)

0.963

Immunocompromised

 No

11/45 (24.4)

    

 Yes

20/83 (24.1)

0.98 (0.42–2.29)

0.965

0.64 (0.19–2.14)

0.474

Haemodynamic status at presentation

 No shock

2/63 (3.2)

    

 In shock

29/65 (44.6)

24.57 (5.50–109.76)

< 0.001

45.77 (10.30–203.41)

< 0.001

Source of bacteraemia b

 Pulmonary

11/20 (55.0)

5.38 (1.96–14.76)

0.001

3.32 (0.96–11.46)

0.058

 Invasive intravascular catheters

2/32 (6.3)

0.15 (0.03–0.69)

0.015

0.18 (0.04–0.90)

0.036

 Urinary tract

1/18 (5.6)

0.16 (0.02–1.24)

0.079

0.17 (0.02–1.32)

0.091

 Skin & soft tissue

2/13 (15.4)

0.54 (0.11–2.59)

0.441

0.88 (0.11–6.99)

0.907

 Unknown

14/41 (34.2)

2.14 (0.92–4.94)

0.076

1.73 (0.67–4.44)

0.256

  1. Abbreviations: OR odds ratio, CI confidence interval, ID infectious diseases specialist
  2. a Adjusted for age, Charlson comorbidity index, IDC, surgical intervention and appropriateness of antimicrobial therapy
  3. b The odds ratio compares odds of death in current group with the odds of death in all other groups combined