Skip to main content

Table 3 Analysis of factors likely to influence 30-day all-cause mortality

From: The impact of infectious diseases consultation on the management and outcomes of Pseudomonas aeruginosa bacteraemia in adults: a retrospective cohort study

Variables Mortality n/Total (%) Unadjusted OR (95% CI) P value Adjusteda OR (95% CI) P value
IDC
 Yes 10/91 (11.0)     
 No 21/37 (56.8) 10.63(4.20–26.89) < 0.001 7.84 (2.95–20.86) < 0.001
Age (years)
 < 65 10/53 (18.9)     
 ≥ 65 21/75 (28.0) 1.67 (0.71–3.94) 0.239 0.69 (0.19–2.44) 0.562
Age (years)
 < 75 15/86 (17.4)     
 ≥ 75 16/42 (38.1) 2.91 (1.26–6.74) 0.012 1.56 (0.50–4.87) 0.441
Gender
 Female 13/59 (22.0)     
 Male 18/69 (26.1) 1.25 (0.55–2.84) 0.595 1.54 (0.56–4.28) 0.407
Charlson comorbidity index
 Score < 5 5/50 (10.0)     
 Score ≥ 5 26/78 (33.3) 4.50 (1.59–12.75) 0.005 5.14 (1.22–21.58) 0.025
Appropriate antibiotic therapy
 Yes 17/88 (19.3)     
 No 14/40 (35.0) 0.44 (0.19–1.03) 0.059 0.38 (0.06–2.26) 0.289
Surgical intervention for source control 2/21 (9.5)     
29/107 (27.1) 3.53 (0.77–16.22) 0.105 2.64 (0.44–15.77) 0.287
Febrile neutropenia
 No 22/83 (26.5)     
 Yes 9/45 (20.0) 0.69 (0.29–1.67) 0.415 0.97 (0.33–2.89) 0.963
Immunocompromised
 No 11/45 (24.4)     
 Yes 20/83 (24.1) 0.98 (0.42–2.29) 0.965 0.64 (0.19–2.14) 0.474
Haemodynamic status at presentation
 No shock 2/63 (3.2)     
 In shock 29/65 (44.6) 24.57 (5.50–109.76) < 0.001 45.77 (10.30–203.41) < 0.001
Source of bacteraemia b
 Pulmonary 11/20 (55.0) 5.38 (1.96–14.76) 0.001 3.32 (0.96–11.46) 0.058
 Invasive intravascular catheters 2/32 (6.3) 0.15 (0.03–0.69) 0.015 0.18 (0.04–0.90) 0.036
 Urinary tract 1/18 (5.6) 0.16 (0.02–1.24) 0.079 0.17 (0.02–1.32) 0.091
 Skin & soft tissue 2/13 (15.4) 0.54 (0.11–2.59) 0.441 0.88 (0.11–6.99) 0.907
 Unknown 14/41 (34.2) 2.14 (0.92–4.94) 0.076 1.73 (0.67–4.44) 0.256
  1. Abbreviations: OR odds ratio, CI confidence interval, ID infectious diseases specialist
  2. a Adjusted for age, Charlson comorbidity index, IDC, surgical intervention and appropriateness of antimicrobial therapy
  3. b The odds ratio compares odds of death in current group with the odds of death in all other groups combined