Table 2 CLSI Breakpoints for Select Penicillin and Cephalosporins [7]
From: Predicting Oral Beta-lactam susceptibilities against Streptococcus pneumoniae
Interpretative Categories and MIC Breakpoints (μg/ml) | |||
|---|---|---|---|
Antimicrobial Agent | Susceptible | Intermediate | Resistant |
Penicillin (meningitis) | ≤ 0.06 | – | ≥ 0.12 |
Penicillin (non-meningitis) | ≤ 2 | 4 | ≥ 8 |
Amoxicillin | ≤ 2 | 4 | ≥ 8 |
Cefotaxime (meningitis) | ≤ 0.5 | 1 | ≥ 2 |
Cefotaxime (non-meningitis) | ≤ 1 | 2 | ≥ 4 |
Cefuroxime (oral) | ≤ 1 | 2 | ≥ 4 |
Cefdinir | ≤ 0.5 | 1 | ≥ 2 |
Cefpodoxime | ≤ 0.5 | 1 | ≥ 2 |