Fig. 4

Serum cytokine expression profile in CHIKV and DENV-infected patients on indicated day of fever. Cytokine levels from CHIKV and DENV-infected patients with available day of fever data were segregated into day 1–2, 3–4, and 5–9 and compared with healthy control (HC) group as well as among other groups. Each dot represents the cytokine concentration of an individual. Bars indicate group median. Assay detection sensitivity limits are indicated by the grey dashed line. Black asterisks represent statistical significance by the Mann-Whitney test (*P < 0.05, **P < 0.01, ***P < 0.001)