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Table 6 Baseline characteristics, clinical presentation, and outcome of patients with K. pneumoniae liver abscess with or without metastatic infections

From: Clinical features and development of Sepsis in Klebsiella pneumoniae infected liver abscess patients: a retrospective analysis of 135 cases

Characteristic Total
n = 135
KPLA with Metastatic infection
n = 12
KPLA without Metastatic infection
n = 123
P value
Age (year) 60.9 ± 12.7 58.3 ± 12.2 61.1 ± 12.8 0.467
Gender     0.494
 Male,n(%) 80 (59.3) 6 (50.0) 74 (60.2)  
 Female,n(%) 55 (40.7) 6 (50.0) 49 (39.8)  
Symptoms
 Body temperature (≥38.5 °C) 80 (59.3) 7 (58.3) 73 (59.3) 0.945
 Fever 123 (91.1) 11 (91.7) 112 (91.1) 1.000a
 Chills 81 (60.0) 8 (66.7) 73 (59.3) 0.621
 Abdominal pain 58 (43.0) 6 (50.0) 52 (42.3) 0.606
 Nausea 17 (12.6) 2 (16.7) 15 (12.2) 0.648a
 Vomiting 16 (11.9) 2 (16.7) 14 (11.4) 0.635a
 Frailty 24 (17.8) 2 (16.7) 22 (17.9) 1.000a
 Diarrhea 9 (6.7) 0 9 (7.3) 1.000a
Underlying conditions
 Diabetes mellitus 67 (50.0) 7 (58.3) 60 (48.8) 0.528
 Hypertension 51 (37.8) 6 (50.0) 45 (36.6) 0.360
 Fatty liver 16 (11.9) 1 (8.3) 15 (12.2) 1.000a
 Cholelithiasis 29 (21.5) 1 (8.3) 28 (22.8) 0.461a
 Viral hepatitis 32 (23.7) 2 (16.7) 30 (24.4) 0.731a
 Cardiovascular diseases 25 (18.5) 3 (25.0) 22 (17.9) 0.696a
 Chronic renal insufficiency 14 (10.4) 5 (41.7) 9 (7.3) 0.000
 Hepatic dysfunction 21 (15.6) 3 (25.0) 18 (14.6) 0.399a
 Abdominal surgery history 9 (6.7) 1 (8.3) 8 (6.5) 0.579a
Abscess location
 Right lobe 90 (66.7) 10 (83.3) 80 (65.0) 0.199
 Left lobe 34 (25.2) 2 (16.7) 32 (26.0) 0.730a
 Both lobes 11 (8.1) 0 11 (8.9) 0.598a
Laboratory findings
 WBC > 9.5× 109/L 105 (77.8) 10 (83.3) 95 (77.2) 0.628
 NE% > 75% 119 (88.1) 12 (100.0) 107 (87.0) 0.359a
 PLT < 125 38 (28.1) 7 (58.3) 31 (25.2) 0.015
 Hb < 110 g/L 37 (27.4) 2 (16.7) 35 (28.5) 0.511a
 CRP > 10 mg/L 127 (94.1) 12 (100.0) 105 (85.4) 0.367a
 PCT > 0.5 ng/ml 120 (88.9) 12 (100.0) 108 (87.8) 0.360a
 ALT > 50 U/L 73 (54.1) 5 (41.7) 68 (55.3) 0.366
 AST > 40 U/L 79 (58.5) 7 (58.3) 72 (58.5) 0.989
 ALP > 125 U/L 100 (74.1) 10 (83.3) 90 (73.2) 0.443
 GGT > 60 U/L 105 (77.8) 8 (66.7) 97 (78.9) 0.332
 T.Bil > 20.5 μmol/L 44 (32.6) 7 (58.3) 37 (30.3) 0.049
 ALB< 40 g/L 129 (95.6) 12 (100.0) 117 (95.1) 1.000a
 FIB> 4 g/L 128 (94.8) 11 (91.7) 117 (95.1) 0.487a
 APTT> 42 s 80 (59.3) 6 (50.0) 74 (60.2) 0.494
 BUN > 7.2 mmol/L 41 (30.4) 8 (66.7) 32 (26.2) 0.003
 Cr > 97 μmol/L 20 (14.8) 5 (41.7) 15 (12.3) 0.006
Treatment     0.075
 Antibiotics alone 7 (5.2) 0 7 (5.7)  
 Antibiotics+Percutaneous drainage 122 (90.4) 10 (83.3) 112 (91.1)  
 Antibiotics+Surgical drainage 6 (4.4) 2 (16.7) 4 (3.3)  
Clinical outcomes     0.007a
 Cured 133 (98.5) 10 (83.3) 123 (100.0)  
 Poor prognosis 2 (1.5) 2 (16.7) 0