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Table 6 Baseline characteristics, clinical presentation, and outcome of patients with K. pneumoniae liver abscess with or without metastatic infections

From: Clinical features and development of Sepsis in Klebsiella pneumoniae infected liver abscess patients: a retrospective analysis of 135 cases

Characteristic

Total

n = 135

KPLA with Metastatic infection

n = 12

KPLA without Metastatic infection

n = 123

P value

Age (year)

60.9 ± 12.7

58.3 ± 12.2

61.1 ± 12.8

0.467

Gender

   

0.494

 Male,n(%)

80 (59.3)

6 (50.0)

74 (60.2)

 

 Female,n(%)

55 (40.7)

6 (50.0)

49 (39.8)

 

Symptoms

 Body temperature (≥38.5 °C)

80 (59.3)

7 (58.3)

73 (59.3)

0.945

 Fever

123 (91.1)

11 (91.7)

112 (91.1)

1.000a

 Chills

81 (60.0)

8 (66.7)

73 (59.3)

0.621

 Abdominal pain

58 (43.0)

6 (50.0)

52 (42.3)

0.606

 Nausea

17 (12.6)

2 (16.7)

15 (12.2)

0.648a

 Vomiting

16 (11.9)

2 (16.7)

14 (11.4)

0.635a

 Frailty

24 (17.8)

2 (16.7)

22 (17.9)

1.000a

 Diarrhea

9 (6.7)

0

9 (7.3)

1.000a

Underlying conditions

 Diabetes mellitus

67 (50.0)

7 (58.3)

60 (48.8)

0.528

 Hypertension

51 (37.8)

6 (50.0)

45 (36.6)

0.360

 Fatty liver

16 (11.9)

1 (8.3)

15 (12.2)

1.000a

 Cholelithiasis

29 (21.5)

1 (8.3)

28 (22.8)

0.461a

 Viral hepatitis

32 (23.7)

2 (16.7)

30 (24.4)

0.731a

 Cardiovascular diseases

25 (18.5)

3 (25.0)

22 (17.9)

0.696a

 Chronic renal insufficiency

14 (10.4)

5 (41.7)

9 (7.3)

0.000

 Hepatic dysfunction

21 (15.6)

3 (25.0)

18 (14.6)

0.399a

 Abdominal surgery history

9 (6.7)

1 (8.3)

8 (6.5)

0.579a

Abscess location

 Right lobe

90 (66.7)

10 (83.3)

80 (65.0)

0.199

 Left lobe

34 (25.2)

2 (16.7)

32 (26.0)

0.730a

 Both lobes

11 (8.1)

0

11 (8.9)

0.598a

Laboratory findings

 WBC > 9.5× 109/L

105 (77.8)

10 (83.3)

95 (77.2)

0.628

 NE% > 75%

119 (88.1)

12 (100.0)

107 (87.0)

0.359a

 PLT < 125

38 (28.1)

7 (58.3)

31 (25.2)

0.015

 Hb < 110 g/L

37 (27.4)

2 (16.7)

35 (28.5)

0.511a

 CRP > 10 mg/L

127 (94.1)

12 (100.0)

105 (85.4)

0.367a

 PCT > 0.5 ng/ml

120 (88.9)

12 (100.0)

108 (87.8)

0.360a

 ALT > 50 U/L

73 (54.1)

5 (41.7)

68 (55.3)

0.366

 AST > 40 U/L

79 (58.5)

7 (58.3)

72 (58.5)

0.989

 ALP > 125 U/L

100 (74.1)

10 (83.3)

90 (73.2)

0.443

 GGT > 60 U/L

105 (77.8)

8 (66.7)

97 (78.9)

0.332

 T.Bil > 20.5 μmol/L

44 (32.6)

7 (58.3)

37 (30.3)

0.049

 ALB< 40 g/L

129 (95.6)

12 (100.0)

117 (95.1)

1.000a

 FIB> 4 g/L

128 (94.8)

11 (91.7)

117 (95.1)

0.487a

 APTT> 42 s

80 (59.3)

6 (50.0)

74 (60.2)

0.494

 BUN > 7.2 mmol/L

41 (30.4)

8 (66.7)

32 (26.2)

0.003

 Cr > 97 μmol/L

20 (14.8)

5 (41.7)

15 (12.3)

0.006

Treatment

   

0.075

 Antibiotics alone

7 (5.2)

0

7 (5.7)

 

 Antibiotics+Percutaneous drainage

122 (90.4)

10 (83.3)

112 (91.1)

 

 Antibiotics+Surgical drainage

6 (4.4)

2 (16.7)

4 (3.3)

 

Clinical outcomes

   

0.007a

 Cured

133 (98.5)

10 (83.3)

123 (100.0)

 

 Poor prognosis

2 (1.5)

2 (16.7)

0