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Table 3 Treatment, complications and outcomes of patients with K. pneumoniae liver abscess with sepsis or without sepsis

From: Clinical features and development of Sepsis in Klebsiella pneumoniae infected liver abscess patients: a retrospective analysis of 135 cases

Characteristic Total
n = 135
KPLA with sepsis
n = 37
KPLA without sepsis
n = 98
P value
Complications
 Sepsis shock 8 (5.9) 7 (18.9) 1 (1.0) 0.000a
 Acute Respiratory Distress Syndrome 4 (3.0) 4 (10.8) 0 0.005a
 Acute kidney injury 2 (1.5) 2 (5.4) 0 0.074 a
 Pleural effusion 11 (8.1) 4 (10.8) 7 (7.1) 0.493 a
 Spontaneous bacterial peritonitis 2 (1.5) 2 (5.4) 0 0.074 a
Metastatic infections
 Lung 11 (8.1) 9 (24.3) 2 (2.0) 0.000a
 Eye 4 (3.0) 4 (10.8) 0 0.005a
 CNS 1 (0.7) 1 (2.7) 0 0.274a
 Others 4 (3.4) 3 (8.1) 1 (1.0) 0.063a
Hospital length of stay, days 14.5 ± 9.0 20.7 ± 9.5 12.2 ± 7.7 0.000
ICU admission 14 (10.4) 11 (29.7) 3 (3.1) 0.000a
Readmission 8 (5.9) 2 (5.4) 6 (6.1) 1.000a
Treatment     0.696
 Antibiotics alone 7 (5.2) 1 (2.7) 6 (6.1)  
 Antibiotics+Percutaneous drainage 122 (90.4) 34 (91.9) 88 (89.8)  
 Antibiotics+Surgical drainage 6 (4.4) 2 (5.4) 4 (4.1)  
Antibiotic drugs
 Beta-lactamase inhibitors 38 (28.1) 18 (48.6) 20 (20.4) 0.001
 The third generation of cephalosporin 59 (43.7) 18 (48.6) 41 (41.8) 0.477
 Fluoroquinolone 51 (37.8) 17 (45.9) 34 (34.7) 0.229
 Carbapenems 96 (71.1) 31 (83.8) 65 (66.3) 0.046
 Metronidazole 57 (42.2) 16 (43.2) 41 (41.8) 0.883
Clinical outcomes     0.074a
 Cured 133 (98.5) 35 (94.6) 98 (100)  
 Died (Poor prognosis) 2 (1.5) 2 (5.4) 0