Pooled sputum to optimise the efficiency and utility of rapid, point-of-care molecular SARS-CoV-2 testing

BMC Infectious Diseases

Table 2 Test performance characteristics for pooled sputum samples on the CovidNudge platform, London, 2020

Legend: 53 patients with positive individual samples were tested with 200 negative results. Pools were either tested as 10 negative samples, or one positive sample with 9 negative samples. An indeterminate result is reported when only one or two replicates amplify, i.e. the signal is at the limits of detection. Pooled samples demonstrated 96.23% sensitivity (95% CI = 87.0–99.5) and 100% specificity (95% CI = 98.2–100) against individual samples

ISSN: 1471-2334