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Table 1 Characteristics of carbapenem-resistant Enterobacteriaceae (CRE)-colonizing strains in different groups

From: Bacterial characteristics of carbapenem-resistant Enterobacteriaceae (CRE) colonized strains and their correlation with subsequent infection

Variables

No. (%) of isolates

 

Infection group (n = 58)

Non-infection group (n = 161)

P

Medical department

 Intensive care unit

23 (39.7)

48 (29.8)

0.170

 Department of haematology

35 (60.3)

113 (70.2)

Species

 Klebsiella pneumoniae

47 (81.0)

86 (53.4)

<  0.001

 ST11

42 (89.4)

26 (30.2)

<  0.001

 ST37

1 (2.1)

10 (11.6)

0.116

 Other ST

4 (8.5)

50 (58.1)

<  0.001

 Escherichia coli

7 (12.1)

47 (29.2)

0.009

 Other CREa

4 (6.9)

28 (17.4)

0.085

MIC of meropenem

 Susceptible

1 (1.7)

15 (9.3)

0.107

 Intermediate

4 (6.9)

12 (7.5)

>  0.999

 Resistant

53 (91.4)

134 (83.2)

0.132

MIC of imipenem

 Susceptible

5 (8.6)

31 (19.3)

0.061

 Intermediate

2 (3.5)

18 (11.2)

0.137

 Resistant

51 (87.9)

112 (69.6)

0.006

MIC of ertapenem

 Susceptible

1 (1.7)

0

0.265

 Intermediate

0

0

 

 Resistant

57 (98.3)

161 (100)

0.265

Carbapenemase

 Positive

51

104

 

 blaKPC-2

42 (72.4)

27 (16.8)

<  0.001

 blaNDMb

9 (15.5)

68 (42.2)

<  0.001

 Otherc

0

9 (5.6)

0.116

 Negative

7 (12.07)

57 (35.4)

0.001

  1. Abbreviations: CRE carbapenem-resistant Enterobacteriaceae; MIC minimum inhibitory concentration
  2. Note:
  3. a Four other CRE in the infection group was Enterobacter cloacae (n = 2), Enterobacter kobei (n = 1) and Morganella morganii (n = 1); 28 other CRE in the Non-infection group was Citrobacter amalonaticus (n = 1), Citrobacter freundii (n = 11), E. cloacae (n = 8), E. kobei (n = 3), Klebsiella oxytoca (n = 2), Raoultella ornithinolytica (n = 2) and Leclercia adecarboxylata (n = 1).
  4. b Nine strains with blaNDM in the infection group was blaNDM-1 (n = 4) and blaNDM-5 (n = 5); 68 strains with blaNDM in the Non-infection group was blaNDM-1 (n = 30), blaNDM-4 (n = 1), blaNDM-5 (n = 35), and blaNDM-7 (n = 2).
  5. c Including two strains co-harbouring blaKPC-2 and blaNDM-1 (K. pneumoniae and K. oxytoca, n = 1), two E. coli with blaVIM-1, two strains with blaIMP-4 (K. pneumoniae and R. ornithinolytica, n = 1), one R. ornithinolytica with blaoxa-48 and two strains which didn’t harbour the tested carbapenemase-encoding genes (E. cloacae and K. pneumoniae, n = 1).
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BMC Infectious Diseases

ISSN: 1471-2334

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