|
Gender, n (%)
|
|
Female
|
126 (22.5)
|
41 (24.1)
|
38 (19.9)
|
47 (23.6)
|
|
Male
|
434 (77.5)
|
129 (75.9)
|
153 (80.1)
|
152 (76.4)
|
|
Age (years), median [IQR]
|
49.00 [41.00, 55.00]
|
48.00 [38.25, 55.00]
|
48.00 [40.50, 54.00]
|
50.00 [43.00, 55.00]
|
|
Risk group, n (%)
|
|
Heterosexual
|
233 (41.6)
|
75 (44.1)
|
76 (39.8)
|
82 (41.2)
|
|
IVDU
|
65 (11.6)
|
16 (9.4)
|
19 (9.9)
|
30 (15.1)
|
|
MSM
|
234 (41.8)
|
71 (41.8)
|
86 (45.0)
|
77 (38.7)
|
|
Other
|
28 (5.0)
|
8 (4.7)
|
10 (5.2)
|
10 (5.0)
|
|
Smoke, n (%)
|
220 (39.3)
|
77 (45.3)
|
65 (34.0)
|
78 (39.2)
|
|
Weight (kg), median [IQR]
|
72.00 [64.00, 80.00]
|
71.50 [63.05, 80.75]
|
73.00 [66.00, 81.00]
|
70.00 [63.00, 78.00]
|
|
BMI, median [IQR]
|
24.01 [21.97, 25.98]
|
23.70 [21.68, 25.86]
|
24.39 [22.49, 26.22]
|
23.94 [21.85, 25.97]
|
|
Systolic blood pressure (mmHg), median [IQR]
|
120.00 [110.00, 130.00]
|
120.00 [110.00, 130.00]
|
120.00 [110.00, 130.00]
|
120.00 [110.00, 130.00]
|
|
Diastolic blood pressure (mmHg), median [IQR]
|
80.00 [70.00, 80.00]
|
80.00 [70.00, 80.00]
|
80.00 [70.00, 80.00]
|
80.00 [70.00, 80.00]
|
|
Previous therapy duration (years), median [IQR]
|
10.36 [4.96, 16.88]
|
9.94 [3.19, 16.22]
|
8.71 [4.56, 15.11]
|
11.47 [6.70, 18.02]
|
|
Previous AIDS, n (%)
|
111 (19.8)
|
39 (22.9)
|
32 (16.8)
|
40 (20.1)
|
|
Treated with ASA, n (%)
|
38 (6.8)
|
9 (5.3)
|
10 (5.2)
|
19 (9.5)
|
|
Treated with anti-hypertensive agent, n (%)
|
101 (18.0)
|
31 (18.2)
|
32 (16.8)
|
38 (19.1)
|
|
Treated with oral hypoglycemic agents / insulin, n (%)
|
18 (3.2)
|
3 (1.8)
|
8 (4.2)
|
7 (3.5)
|
|
Treated with lipid-lowering agents other than statins a, n (%)
|
43 (7.7)
|
16 (9.4)
|
12 (6.3)
|
15 (7.5)
|
|
Treated with statins, n (%)
|
88 (15.7)
|
27 (15.9)
|
33 (17.3)
|
28 (14.1)
|
|
HCV, n (%)
|
121 (21.6)
|
28 (16.5)
|
40 (20.9)
|
53 (26.6)
|
|
HBV, n (%)
|
25 (4.5)
|
14 (8.2)
|
6 (3.1)
|
5 (2.5)
|
|
Switch from PI, n (%)
|
137 (24.6)
|
42 (24.7)
|
13 (6.8)
|
82 (41.6)
|
|
Switch from TDF, n (%)
|
357 (64.1)
|
132 (77.6)
|
167 (87.9)
|
58 (29.4)
|
|
Switch from RTV / cobi, n (%)
|
193 (34.5)
|
113 (66.5)
|
16 (8.4)
|
64 (32.2)
|
|
Switch from INI, n (%)
|
143 (25.5)
|
97 (57.1)
|
5 (2.6)
|
41 (20.6)
|
|
CD4+ (cells/mmc), median [IQR]
|
710.50 [560.00, 893.00]
|
681.00 [535.00, 878.75]
|
711.00 [566.50, 862.00]
|
744.00 [580.00, 961.00]
|
|
Creatinine (mg/dl), median [IQR]
|
0.90 [0.79, 1.03]
|
0.90 [0.79, 1.01]
|
0.94 [0.80, 1.04]
|
0.89 [0.76, 1.04]
|
|
eGFR ml/min, median [IQR]
|
98.49 [79.96, 118.06]
|
97.31 [80.67, 118.45]
|
101.24 [81.70, 115.49]
|
96.92 [75.87, 118.96]
|
|
Triglycerides (mg/dl), median [IQR]
|
115.00 [87.00, 166.00]
|
110.50 [88.50, 169.25]
|
110.50 [81.25, 150.25]
|
122.00 [91.00, 173.00]
|
|
Total cholesterol (mg/dl), median [IQR]
|
193.00 [171.00, 215.00]
|
192.50 [173.75, 213.50]
|
186.00 [169.00, 209.00]
|
200.00 [174.00, 224.00]
|
|
HDL cholesterol (mg/dl), median [IQR]
|
43.00 [37.00, 52.00]
|
43.00 [35.50, 54.00]
|
43.00 [37.00, 49.50]
|
44.00 [36.00, 52.00]
|
|
LDL cholesterol (mg/dl), median [IQR]
|
120.30 [101.40, 143.05]
|
121.80 [102.00, 140.80]
|
115.80 [100.75, 139.50]
|
121.20 [102.40, 153.90]
|
|
Framingham risk score, median [IQR]
|
8.25 [4.19, 16.03]
|
9.18 [3.92, 18.02]
|
7.23 [3.47, 14.11]
|
9.23 [5.13, 15.99]
|
