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Table 2 Frequency distribution of MBL2 and TOLLIP gene polymorphisms in HIV infected patients and healthy controls

From: Genetic association of TOLLIP gene polymorphisms and HIV infection: a case-control study

Gene SNPs Allele/ Genotype Case group N(%) Control group N(%) OR(95%CI) P ORa(95% CI) Pa
MBL2 gene rs7096206(C > G) Allele       
   C 714 (0.820) 1678 (0.831) 1 Reference 1 Reference
  G 156 (0.179) 340 (0.168) 0.998 (0.820–1.214) 0.983 1.050 (0.853–1.294) 0.644
  Genotype       
  CC 293 (0.673) 706 (0.699) 1 Reference 1 Reference
  GC 128 (0.294) 266 (0.263) 1.159 (0.902–1.490) 0.248 1.170 (0.899–1.521) 0.243
  GG 14 (0.032) 37 (0.036) 0.955 (0.697–1.308) 0.774 1.023 (0.734–1.426) 0.892
rs1800450(C > T) Allele       
  C 735 (0.846) 1667 (0.826) 1 Reference 1 Reference
  T 133 (0.153) 351 (0.173) 0.855 (0.699–1.045) 0.127 0.886 (0.716–1.096) 0.266
  Genotype       
  CC 312 (0.718) 689 (0.682) 1 Reference 1 Reference
  TC 111 (0.255) 289 (0.286) 0.848 (0.656–1.096) 0.208 0.860 (0.658–1.125) 0.271
  TT 11 (0.025) 31 (0.030) 0.885 (0.624–1.257) 0.495 0.901 (0.624–1.301) 0.578
TOLLIP gene rs5743899(T > C) Allele       
   T 504 (0.581) 1268 (0.628) 1 Reference 1 Reference
  C 362 (0.418) 750 (0.371) 1.196 (1.026–1.393) 0.022 1.231 (1.048–1.446) 0.011
  Genotype       
  TT 149 (0.344) 409 (0.405) 1 Reference 1 Reference
  CT 206 (0.475) 450 (0.445) 1.257 (0.979–1.613) 0.073 1.274 (0.980–1.655) 0.070
  CC 78 (0.180) 150 (0.148) 1.195 (1.012–1.410) 0.036 1.198 (1.008–1.424) 0.040
rs3750920(C > T) Allele       
  C 607 (0.700) 1391 (0.689) 1 Reference 1 Reference
  T 259 (0.299) 627 (0.310) 0.960 (0.816–1.129) 0.622 0.949 (0.799–1.126) 0.547
  Genotype       
  CC 207 (0.478) 486 (0.481) 1 Reference 1 Reference
  TC 193 (0.445) 419 (0.415) 1.081 (0.854–1.369) 0.515 0.999 (0.780–1.279) 0.994
  TT 33 (0.076) 104 (0.103) 0.863 (0.698–1.067) 0.174 0.861 (0.690–1.075) 0.186
rs5743867(A > G) Allele       
  A 503 (0.590) 1290 (0.639) 1 Reference 1 Reference
  G 349 (0.409) 728 (0.360) 1.356 (1.175–1.564) < 0.001 1.387 (1.191–1.615) < 0.001
  Genotype       
  AA 152 (0.356) 424 (0.420) 1 Reference 1 Reference
  GA 199 (0.467) 442 (0.438) 1.256 (0.978–1.612) 0.074 1.285 (0.0.989–1.669) 0.060
  GG 75 (0.176) 143 (0.141) 1.210 (1.023–1.430) 0.026 1.222 (1.026–1.455) 0.012
  1. Abbreviation: MBL2 mannose binding lectin 2; TOLLIP toll-interacting protein; SNPs single nucleotide polymorphisms; OR odds ratio; CI confidence interval; a, adjusted for age and gender