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Table 2 cfNGS Test Profile

From: Clinical application of cell-free next-generation sequencing for infectious diseases at a tertiary children’s hospital

Total cfNGS tests obtained

n = 142

%

Primary Testing Indication

 

Clinical symptoms suggestive of infection

68

47.9%

 

Focal imaging finding

38

26.8%

 

Infection monitoring

15

10.6%

 

Immunocompromised

9

6.3%

 

Validation of conventional testing

6

4.2%

 

Elevated inflammatory markers

3

2.1%

 

Suspected rheumatologic process

3

2.1%

Median hospital day sent (IQR)

6

(3–28.75)

Hours to results

 

Mean (SD)

85.7

(38.9)

 

Median (IQR)

72

(48–105)

 

Mode

48

 

Results

 

n

%

 

Positive

105

73.9%

 

Single organism

46

 
 

Multiple organisms

59

 
 

Negative

37

26.1%