Skip to main content

Table 2 Comparison of clinical and laboratory features among different age groups in pediatric patients with COVID-19

From: Clinical, laboratory, and chest CT features of severe versus non-severe pediatric patients with COVID-19 infection among different age groups

  Total Age class 1 (0–2) Age class 2 (3–12) Age class 3 (13–17) P- value
N Mean (SD)/percentage N Mean (SD)/percentage N Mean (SD)/percentage N Mean (SD)/percentage
Severe
Severe 25 47.2% 5 71.4% 14 51.9% 6 31.6% 0.15
Non-severe 28 52.8% 2 28.6% 13 48.1% 13 68.4%
Sex
Male 22 41.5% 1 14.3% 13 48.1% 8 42.1% 0.27
Female 31 58.5% 6 85.7% 14 51.9% 11 57.9%  
Disease onset to hospital admission duration 53 4.47 (3.55) 7 4.43 (4.31) 27 4.70 (3.58) 19 4.16 (3.38) 0.89
Hospital duration 53 5.37 (4.22) 7 4.00 (2.16) 27 6.07 (3.94) 19 4.89 (5.08) 0.07
ICU duration 53 0.69 (2.46) 7 0.85 (1.57) 27 1.00 (3.26) 19 0.21 (0.91) 0.31
ICU admission
Yes 6 11.3% 2 28.6% 3 11.1% 1 5.3% 0.25
No 47 88.7% 5 71.4% 24 88.9% 18 94.7%
Fever
Yes 42 79.2% 4 57.1% 24 88.9% 14 73.7% 0.14
No 11 20.8% 3 42.9% 3 11.1% 5 26.3%
Dry cough
Yes 40 75.5% 7 100.0% 17 63.0% 16 84.2% 0.07
No 13 24.5% 0 0.0% 10 37.0% 3 15.8%
Nasal congestion
Yes 5 9.4% 2 28.6% 3 11.1% 0 0.0% 0.08
No 48 90.6% 5 71.4% 24 88.9% 19 100.0%
Poor feeding
Yes 2 3.8% 2 28.6%
No 51 96.2% 5 71.4%
Body pain
Yes 14 30.4% 5 18.5% 9 47.4% 0.04
No 32 69.6% 22 81.5% 10 52.6%
Nausea
Yes 12 26.1% 8 29.6% 4 21.1% 0.51
No 34 73.9% 19 70.4% 15 78.9%
Diarrhea
Yes 5 9.4% 0 0.0% 3 11.1% 2 10.5% 0.66
No 48 90.6% 7 100.0% 24 88.9% 17 89.5%
Vomiting
Yes 11 20.8% 0 0.0% 8 29.6% 3 15.8% 0.18
No 42 79.2% 7 100.0% 19 70.4% 16 84.2%
Abdominal pain
Yes 3 6.5% 2 7.4% 1 5.3% 0.77
No 43 93.5% 25 92.6% 18 94.7%
Distress
Yes 23 43.4% 5 71.4% 13 48.1% 5 26.3% 0.09
No 30 56.6% 2 28.6% 14 51.9% 14 73.7%
Outcome
Dead 1 1.9% 0 0.0% 1 3.7% 0 0.0% 0.61
Alive 52 98.1% 7 100.0% 26 96.3% 19 100.0%
Leukocyte count, × 109/L 53 9232.08 (4755.19) 7 10,085.71 (2848.05) 27 9085.19 (5532.67) 19 9126.32 (4251.64) 0.48
Leukopenia (< 3.5 × 109/L)
Yes 3 5.7% 0 0.0% 3 11.1% 0 0.0% 0.22
No 50 94.3% 7 100.0% 24 88.9% 19 100.0%
Leukocytosis (> 11 × 109/L)
Yes 17 32.1% 4 57.1% 9 33.3% 4 21.1% 0.21
No 36 67.9% 3 42.9% 18 66.7% 15 78.9%
Lymphocyte, % 53 26.24 (13.17) 7 30.95 (12.65) 27 26.67 (13.71) 19 23.90 (12.71) 0.37
Lymphopenia (< 20%)
Yes 21 39.6% 1 14.3% 10 37.0% 10 52.6% 0.19
No 32 60.4% 6 85.7% 17 63.0% 9 47.4%
Lymphocytosis (> 40%)
Yes 7 13.2% 2 28.6% 3 11.1% 2 10.5% 0.43
No 46 86.8% 5 71.4% 24 88.9% 17 89.5%
CRP, mg/L 53 40.13 (45.93) 7 4.57 (5.71) 27 50.93 (45.82) 19 37.89 (48.80) 0.01
ESR, mm/h 16 34.75 (29.03) 2 22.50 (2.12) 10 46.20 (31.55) 4 12.25 (3.86) 0.05
O2 saturation, % 51 93.61 (5.89) 7 87.14 (9.70) 26 93.62 (4.99) 18 96.11 (2.90) 0.01
Antiviral therapy
Yes 11 20.8% 1 14.3% 4 14.8% 6 31.6% 0.35
No 42 79.2% 6 85.7% 23 85.2% 13 68.4%
Antibacterial therapy
Yes 49 92.5% 7 100.0% 26 96.3% 16 84.2% 0.22
No 4 7.5% 0 0.0% 1 3.7% 3 15.8%
Comorbid disease
Comorbid disease
  Yes 20 37.7% 3 42.9% 10 37.0% 7 36.8% 0.96
  No 33 62.3% 4 57.1% 17 63.0% 12 63.2%
G6PD deficiency
  Yes 4 7.5% 1 14.3% 1 3.7% 2 10.5% 0.53
  No 49 92.5% 6 85.7% 26 96.3% 17 89.5%
Cardiovascular
  Yes 3 5.7% 2 28.6% 1 3.7% 0 0.0% 0.02
  No 50 94.3% 5 71.4% 26 96.3% 19 100.0%
Gastrointestinal
  Yes 3 5.7% 0 0.0% 2 7.4% 1 5.3% 0.75
  No 50 94.3% 7 100.0% 25 92.6% 18 94.7%
Other comorbid diseases
  Yes 6 11.3% 0 0.0% 3 11.1% 3 15.8% 0.53
  No 47 88.7% 7 100.0% 24 88.9% 16 84.2%
  1. CRP, C-reactive protein; ESR, erythrocyte sedimentation rate. Continuous and categorical variables were analyzed using independent t-test/Mann-Whitney U test and χ2/Fisher’s exact tests, respectively. P-value less than 0.05 was considered as significant