Skip to main content

Table 1 Clinical characteristics of severely-symptomatic COVID-19 patients, mildly-symptomatic COVID-19 patients and non SARS-CoV-2 infected control subjects

From: Vitamin D and COVID-19 severity and related mortality: a prospective study in Italy

 

Whole cohort

(N = 361)

Non SARS-CoV-2 infected Control

(N = 206)

Mildly symptomatic COVID-19

(n = 52)

Severely Symptomatic COVID-19

(n = 103)

P-value

Age, years median [IQR]

66.00

[54.00–78.00]

67.00

[57.00–77.00]

57.50

[51.00–86.05]

66.70

[56.10–77.40]

0.649 ǂ

Male N(%)

243 (67%)

142 (69%)

31 (60%)

70 (68%)

0.435†

CV disease a N(%)

54 (15%)

31 (15%)

11 (21%)

12 (12%)

0.293†

At least 1 comorbidity b N(%)

181 (50%)

95 (46%)

23 (44%)

63 (61%)

0.03†

 Obesity N (%)

67 (19%)

42 (20%)

5 (10%)

20 (19%)

0.196†

 Diabetes N (%)

61 (17%)

31 (15%)

11 (21%)

19 (18%)

0.510†

 Hypertension N (%)

140 (39%)

75 (36%)

13 (25%)

52 (51%)

0.005†

vitamin D deficiency

(25OHD ≤20 ng/mL) N(%)

127 (35%)

57 (28%)

6 (12%)

64 (62%)

< 0.0001†

25OHD ng/mL mean (SD)

24.0 (10.6)

25.4 (9.4)

30.3 (8.4)

18.2 (11.4)

< 0.0001‡

  1. IQR Interquartile range; SD Standard Deviation; CV Cardiovascular; ǂ = Kruskal-Wallis test; † = Chi square test; ‡ = ANOVA model;
  2. a cardiovascular disease: coronary heart disease, stroke, myocardial infarction; b at least 1 comorbidity among obesity, diabetes, arterial hypertension