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Table 1 Patients’ characteristics at baseline

From: Therapeutic prediction of HIV-1 DNA decay: a multicenter longitudinal cohort study

Characteristics Training cohort (n = 490) Validation cohort (n = 117)
Median age (years, IQR) 35 (28–44) 32 (28–43)
Gender (n, %)
 Male 342 (69.8) 108 (92.3)
 Female 148 (30.2) 9 (7.7)
Transmission category (n, %)
 MSM 154 (31.4) 84 (71.8)
 Heterosexual 258 (52.7) 18 (15.4)
 Bisexual 14 (2.9) 4 (3.4)
 Blood 7 (1.4) 0 (0)
 Others/Unknown 57 (11.6) 11 (9.4)
Subtype (n, %)   NA
 CRF01_AE 218 (44.5)  
 C/CRF07_BC/CRF08_BC 123 (25.1)  
 B/B′ 55 (11.2)  
 URF 18 (3.7)  
 Unknown 76 (15.5)  
Median CD4 cell count (cells/μL, IQR) 226 (159–344) 189 (50–293)
Median CD8 cell count (cells/μL, IQR) 809 (590–1181) 627 (449–925)
Median CD4/CD8 ratio (IQR) 0.25 (0.18–0.40) 0.27 (0.13–0.45)
Median HIV-1 plasma RNA (log copies/mL, IQR) 4.66 (4.34–5.14) 4.48 (2.90–4.96)
Median total HIV-1 DNA (log copies/106 PBMCs, IQR) 3.00 (2.66–3.33) 3.01 (2.74–3.29)
  1. Note: IQR interquartile range, MSM men who have sex with men, NA not applicable, CRF circulating recombinant form, PBMCs peripheral blood mononuclear cells