Table 1 Patients’ characteristics at baseline
From: Therapeutic prediction of HIV-1 DNA decay: a multicenter longitudinal cohort study
Characteristics | Training cohort (n = 490) | Validation cohort (n = 117) |
|---|---|---|
Median age (years, IQR) | 35 (28–44) | 32 (28–43) |
Gender (n, %) | ||
 Male | 342 (69.8) | 108 (92.3) |
 Female | 148 (30.2) | 9 (7.7) |
Transmission category (n, %) | ||
 MSM | 154 (31.4) | 84 (71.8) |
 Heterosexual | 258 (52.7) | 18 (15.4) |
 Bisexual | 14 (2.9) | 4 (3.4) |
 Blood | 7 (1.4) | 0 (0) |
 Others/Unknown | 57 (11.6) | 11 (9.4) |
Subtype (n, %) | Â | NA |
 CRF01_AE | 218 (44.5) |  |
 C/CRF07_BC/CRF08_BC | 123 (25.1) |  |
 B/B′ | 55 (11.2) |  |
 URF | 18 (3.7) |  |
 Unknown | 76 (15.5) |  |
Median CD4 cell count (cells/μL, IQR) | 226 (159–344) | 189 (50–293) |
Median CD8 cell count (cells/μL, IQR) | 809 (590–1181) | 627 (449–925) |
Median CD4/CD8 ratio (IQR) | 0.25 (0.18–0.40) | 0.27 (0.13–0.45) |
Median HIV-1 plasma RNA (log copies/mL, IQR) | 4.66 (4.34–5.14) | 4.48 (2.90–4.96) |
Median total HIV-1 DNA (log copies/106 PBMCs, IQR) | 3.00 (2.66–3.33) | 3.01 (2.74–3.29) |