|
Relative hazards of AIDS/SNAE/death
|
---|
hs-CRP, mg/L
|
Unadjusted RH (95% CI)
|
p-value
|
Adjusteda RH (95% CI)
|
p-value
|
Adjustedb RH (95% CI)
|
p-value
|
---|
All patients (n = 375)
|
0.0–1.1
|
1
| |
1
| |
1
|
Global
|
| | | | | |
0.002
|
1.2–5.3
|
1.42 (0.88, 2.27)
|
0.147
|
1.50 (0.89, 2.52)
|
0.127
|
1.61 (0.95, 2.73)
|
0.078
|
5.4+
|
1.85 (1.09, 3.15)
|
0.023
|
1.59 (0.88, 2.89)
|
0.128
|
1.69 (0.92, 3.11)
|
0.093
|
per natural log higher
|
1.12 (0.99, 1.27)
|
0.065
|
1.06 (0.89, 1.25)
|
0.539
|
1.12 (0.93, 1.36)
|
0.238
|
Complete case analysisc (n = 208)
|
0.0–1.1
|
1
| |
1
| |
1
|
Global
|
| | | | | |
0.07
|
1.2–5.3
|
1.15 (0.60, 2.20)
|
0.674
|
1.39 (0.66, 2.91)
|
0.386
|
1.70 (0.77, 3.76)
|
0.189
|
5.4+
|
1.43 (0.67, 3.06)
|
0.352
|
1.01 (0.41, 2.51)
|
0.982
|
1.29 (0.49, 3.42)
|
0.608
|
per natural log higher
|
1.11 (0.93, 1.32)
|
0.242
|
1.06 (0.89, 1.25)
|
0.539
|
1.12 (0.93, 1.36)
|
0.238
|
Restricting to people with hs-CRP lower than 10 mg/L (n = 335)
|
0.0–1.1
|
1
| |
1
| |
1
|
Global
|
| | | | | |
0.002
|
1.2–5.3
|
1.40 (0.88, 2.25)
|
0.158
|
1.56 (0.92, 2.64)
|
0.098
|
1.78 (1.05, 3.04)
|
0.034
|
5.4+
|
1.28 (0.59, 2.79)
|
0.535
|
1.42 (0.57, 3.49)
|
0.451
|
1.42 (0.57, 3.56)
|
0.453
|
per natural log higher
|
1.02 (0.87, 1.21)
|
0.779
|
1.08 (0.84, 1.39)
|
0.562
|
1.12 (0.86, 1.47)
|
0.405
|
- aadjusted forage, CD4, VL, HCV/HBV, year of cART, duration of HIV infection at starting cART,type of cART started as well as all other biomarkers
- badjusted forage, mode of HIV transmission, alcohol consumption, smoking, CD4, VL, HCV/HBV, year of cART, duration of HIV infection at starting cART,type of cART started as well as all other biomarkers
- ccomplete data for all four biomarkers