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Table 3 Comparison of laboratory findings between group TMP and group TMN during the first visit

From: Clinical findings of Talaromyces marneffei infection among patients with anti-interferon-γ immunodeficiency: a prospective cohort study

Variable

Group TMP (N = 22)

Group TMN (N = 20)

P value

White cell count (*109 cells/L)

13.4 (9.3, 18.0)

7.7 (5.8, 12.0)

0.012

Absolute neutrophil count (*109 cells/L)

10.7 (6.9, 13.3)

5.1 (3.6, 11.4)

0.019

Neutrophil ratio (neut %)

0.76 (0.7, 0.9)

0.7 (0.6, 0.8)

0.120

Eosinophil count (*109 cells/L)

0.4 (0.1, 0.6)

0.1 (0.1, 0.3)

0.030

Hemoglobin (g/L)

89.7 (69.0,123.8)

111.0 (93.8129.8)

0.049

Platelet count (*109 cells/L)

310.5 (226.2485.7)

312.0 (189.0,408.0)

0.569

Erythrocyte sedimentation rate (mm/h)a

98.0 (72.0, 102.0)

52.0 (15.9, 88.0)

0.008

C-reactive protein (mg/dL)b

7.7 (3.3, 15.7)

72.5 (14.9, 137.2)

0.002

Immunoglobulinc

 Ig G (g/L)

28.7 (17.5, 34.0)

17.7 (13.7, 25.8)

0.026

 Ig A (g/L)

1.1 (0.8,1.5)

1.2 (0.9,2.2)

0.400

 Ig M (g/L)

2.6 (1.5, 2.8)

2.2 (1.5,2.9)

0.880

T cell countd

 CD3+ T cell count (cells/μl)

1425.0 (109.1, 1945.0)

830.5 (355.51302.3)

0.011

 CD4+ T cell count (cells/μl)

685.0 (419.0, 965.5)

433.0 (111.3844.5)

0.247

 CD8+ T cell count (cells/μl)

631.0 (499.0, 1132.0)

333.5 (151.0, 467.0)

<0.001

  1. aErythrocyte sedimentation rate data were missing for 8 patients (19%)
  2. bC-reactive protein data were missing for 12 patients (28.5%)
  3. cImmunoglobulin data were missing for 10 patients (23.8%)
  4. dT cell count data were missing for 17 patients (40.5%)
  5. Group TMP = anti-IFN-γ autoantibody-positive group
  6. Group TMN = anti-IFN-γ autoantibody-negative group