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Table 4 Resistance and virulence profile of isolates from bacteremic children who died after admission

From: Klebsiella spp. cause severe and fatal disease in Mozambican children: antimicrobial resistance profile and molecular characterization

Isolate ID

Resistance profile

Virurence profile

Antibiotherapy

Co-infection

Days of hospitalization

392.5

AMP-AMK-AUG-CRO-CAZ-ATM-SXT-CHL-CXM

fimH-mrkD-entB-blaCTX-M-15

Unkown

 

2

034.5

AMP-AUG

fimH-hylA-mrkD-ycfM-entB

Unkown

 

1

8055

AMP-GEN-SXT

ycfM-pet-entB

Unkown

 

6

937.6

AMP-AUG-CRO-ATM-GEN-TOB-SXT-CHL-CXM

mrkD-ycfM-entB-blaTEM-1

Unkown

 

1

208.4

AMP-SXT

No virulence genes

Aminoglycosides-ampicillin/amoxicillin

Streptococcus group D

1

580.4

AMP-AUG-CRO-ATM-GEN-TOV-SXT-CL-CXM

mrkD-ycfM-entB-wzi-K1

Chloramphenicol

 

4

439.9

AMP-AUG-CRO-ATM-GEN-TOB-SXT-CHL-CXM

mrkD-ycfM-entB-blaSHV-1

Chloramphenicol- Aminoglycosides-ampicillin/amoxicillin

Pseudomonas aeruginosa

3

522.4

AMP

fimH-hylAI-ycfM-sat-entB

Aminoglycosides-ampicillin/amoxicillin

Staphylococcus aureus

1

563.7

AMP

mrkD-ycfM-traT

Chloramphenicol

 

2

676.9

AMP-AUG-CRO-ATM-GEN-SXT-CHL-CXM

fimH-hylA-mrkD-sat-entB-trat-hylC-blaTEM-1

Aminoglycosides

 

1

785.3

AMP-AMK-AUG-CRO-ATM-GEN-TOB-SXT-CHL-CXM

mrkD-ycfM-sigA-entB-blaCTX-M-15-blaSHV-1

Cotrimaxozol

 

3

520.4

AMP-AUG-CRO-GEN-SXT-CHL-CXM

fimH-mrkD-ycfM-entB-blaCTX-M-15-

Penicillin-aminoglycosides-cephalosporin

 

15

401.8

AMP

fmH-mrkD

Cotrimaxozol-aminoglycosides-ampicillin/amoxixillin-cephalosporin

 

1

009.1

AMP-AUG_CRO-CAZ-GEN-SXT-CHL-CXM

hylA-mrkD-entB-traT-hylC-blaCTX-M-15-blaSHV-1

Aminoglycoside-ampicillin/amoxicillin

 

1

073.2

AMP-AUG-CRO-ATM-GEN-SXT-CHL-CXM

mrkD-ycfM-entB-rmpA

Cotrimaxozol-aminoglycoside-ampicillin/amoxicillin-cephalosporin

 

18

334.2

AMP

mrkD-ycfM

Cotrimaxozol-chloramphenicol-aminoglycoside-ampicillin/amoxicillin

 

12

908.4

AMP-AUG-CAZ-GEN-TOB-SXT-CHL

fimH-mrkD-saT-sepA-piC-entB-hylC

Penicillin-cotrimaxozol-aminoglycoside

 

9

909.1

AMP-SXT

entB

Penicillin-aminoglicoside

 

4

9285

AMP-CRO-CAZ-ATM-GEN-NA-SXT-CHL-CXM

entB- blaSHV-1

Cotrimaxozol-aminoglycoside-ampicillin/amoxicillin-cephalosporin

 

3

657.9

AMP-AUG-CRO-CAZ-ATM-TOB-NA-CIP-SXT-CHL-CXM

fimH-saT-peT- blaCTX-M-231-blaSHV-1

Aminoglycoside-ampicillin/amoxicillin

 

1

143.8

AMP

fimH

Chloramphenicol-aminoglycoside-ampicillin/amoxicillin

 

1

522.4

AMP

fimH-mrkD-entB

Cephalosporin

 

6

218.4

AMP-AUG-CRO-ATM-GEN-TOB-SXT-CHL-CXM

ycfM-saT-entB-hylC- blaCTX-M-15

Aminoglycoside-ampicillin/amoxicillin

 

1

  1. AMP Ampicillin, AMK Amikacin, AUG Amoxicillin-clavulanic acid, TZP Piperacillin-tazobactam, CXM Cefuroxime, CRO Ceftriaxone, CAZ Ceftazidime, ATM Aztreonam, ETP Ertapenem, IPM Imipenem, MEM Meropenem, NA Nalidixic acid, CIP Ciprofloxacin, CHL Chloramphenicol, GEN Gentamicin, TOB Tobramycin, TET Tetracycline, SxT Trimethoprim- Sulfamethoxazole, MDR Multi-drug resistant (defined when isolates are resistant ≥3 unrelated antibiotic groups), ESBL – Extended-spectrum β-lactamase phenotype
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BMC Infectious Diseases

ISSN: 1471-2334

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