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Table 2 Antimicrobial resistance profile of Klebsiella isolates recovered from blood samples collected upon admission and postmortem blood samples

From: Klebsiella spp. cause severe and fatal disease in Mozambican children: antimicrobial resistance profile and molecular characterization

 

On admission n = 88(%)

Postmortem n = 23(%)

P value

AMP

82 (93.1)

21 (91.3)

1

AMK

2 (2.3)

0

0.462

AUG

44 (50)

13 (56.5)

0.607

TZP

1 (1.1)

1 (4.3)

0.321

CXM

43 (48.9)

15 (65.2)

0.162

CRO

43 (48.9)

16 (69.6)

0.045

CAZ

18 (20.4)

15 (65.2)

0.001

ATM

42 (47.7)

12 (52.2)

0.526

ETP

0

8 (34.8)

< 0.0001

IPM

0

0

 

MEM

0

3 (13)

0.009

NA

9 (10.2)

4 (17.4)

0.464

CIP

10 (11.4)

9 (39.1)

0.012

CHL

44 (50)

6 (26.1)

0.04

GEN

44 (50)

16 (69.6)

0.094

TOB

37 (42.1)

14 (60.9)

0.112

TET

30 (34.1)

6 (26.1)

0.521

SxT

68 (77.3)

11 (47.8)

0.233

MDR

58 (65.9)

16 (69.6)

0.741

ESBL

22 (25)

14 (60.9)

0.001

  1. AMP Ampicillin, AMK Amikacin, AUG Amoxicillin-clavulanic acid, TZP Piperacillin-tazobactam, CXM Cefuroxime, CRO Ceftriaxone, CAZ Ceftazidime, ATM Aztreonam, ETP Ertapenem, IPM Imipenem, MEM Meropenem, NA Nalidixic acid, CIP Ciprofloxacin, CHL Chloramphenicol, GEN Gentamicin, TOB Tobramycin, TET Tetracycline, SxT Trimethoprim- Sulfamethoxazole, MDR Multi-drug resistant (defined when isolates are resistant ≥3 unrelated antibiotic groups), ESBL – Extended-spectrum β-lactamase phenotype