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Table 3 Univariate logistic regression analysis of variables investigated for prediction of MDR gram-negative infection in cancer patients with bloodstream infection

From: Bloodstream infections in adult patients with malignancy, epidemiology, microbiology, and risk factors associated with mortality and multi-drug resistance

 

Non-MDR (n = 19,50.4%)

MDR (n = 188, 49.6%)

OR (95% CI)

p-value

Sex

 Female

78 (40.8)

95 (50.5)

1.48 (0.986, 2.221)

0.059

 Male*

113 (59.2)

93 (49.5)

Age

  < 60

125 (65.4)

136 (72.3)

1.381 (0.892,2.138)

0.148

  > 60*

66 (34.6)

52 (27.7)

Malignancy

 Solid organ tumor

84 (44)

83 (44.1)

1.007 (0.671,1.511)

0.973

 Hematologic malignancy*

107 (56)

105 (55.9)

 ESR

67.96 (34.76)

75.40 (37.68)

1.006 (0.999,1.013)

0.101

 CRP

78.60 (37.28)

88.05 (43.48)

1.006 (1.000,1.012)

0.065

WBC count

  < 4000/μl

97 (51.3)

122 (64.9)

1.753 (1.159,2.651)

0.008

  > 4000/μl*

92 (48.7)

66 (35.1)

Neutropenia

 Yes (< 1500/μl)

69 (36.7)

86 (46.2)

1.483 (0.981,2.243)

0.062

 No (> 1500/μl) *

119 (63.3)

100 (53.8)

Febrile neutropenia

 No*

47 (24.6)

59 (31.4)

1.401 (0.893,2.200)

0.142

 Yes

144 (75.4)

129 (68.6)

Year

 2015

24 (12.6)

18 (9.6)

0.960 (0.429,2.146)

0.921

 2016

32 (16.8)

31 (16.5)

1.240 (0.604,2.546)

0.558

 2017

51 (26.7)

52 (27.7)

1.305 (0.681,2.501)

0.422

 2018

52 (27.2)

62 (33)

1.526 (0.805,2.894)

0.195

 2019*

32 (16.8)

25 (13.3)

  

Enterobacterales

 No **

44 (81.5)

110 (58.8)

3.120 (1.481,6.575)

0.003

 Yes*

10 (18.5)

78 (41.5)

  
  1. * Reference
  2. ** non-fermenter gram-negative BSI. P-values marked with bold indicate statistically significant p-values