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Table 4 The correlation between the top seven common high-risk HPV genotypes and multicentric lesions detection

From: Human papillomavirus genotypes and the risk factors associated with multicentric intraepithelial lesions of the lower genital tract: a retrospective study

HPV genotypes

No. of multicentric lesions, n (%)

Univariable analysis

OR (95% CI)

Adjusting for menopause, smoking, gravidity and etc. * OR (95% CI)

HPV16, n = 407

69(17.0)

0.90 (0.65–1.26)

0.93 (0.66–1.31)

HPV53, n = 75

24(32.0)

2.35 (1.40–3.93)

1.61 (0.92–2.81)

HPV58, n = 137

22(16.1)

0.86 (0.53–1.41)

0.83 (0.50–1.39)

HPV52, n = 142

19(13.4)

0.68 (0.41–1.13)

0.56 (0.32–0.97)

HPV51, n = 52

17(32.7)

2.37 (1.29–4.33)

1.97 (1.04–3.75)

HPV56, n = 62

17(27.4)

1.82 (1.01–3.26)

1.59 (0.85–2.98)

HPV18, n = 84

16(19.0)

1.09 (0.62–1.93)

1.09 (0.60–1.98)

  1. * adjusted for menopause, smoking, gravidity, parity, a history of malignant tumor beyond the lower genital tract and multiple HPV infection
  2. HPV, human papillomavirus