Table 1 Schedule of study visits and sample collections

Risk Exposure Questionnaire

Monthly

Monthly

Quarterly ^b

Semiannually

Symptoms Review Questionnaire

Baseline and daily if symptoms present

B-monthly, or daily if symptoms present

–

–

Saliva for Coronavirus IgA

1 × 0.3 ml

0–1 × 0.3 ml^a

0–1 × 0.3 ml^a

0–1 × 0.3 ml^a

Seurm Separator Tubes (SST) for CoVID multiplex serology analysis

1 × 7.5 ml

1 × 7.5 ml

1 × 7.5 ml

1 × 7.5 ml

Mononuclear Cell Preparation Tube (CPT Na Citrate or CPT Na heparin) for PBMCs and plasma isolation

4–6 × 8 ml

0–6 × 8 ml^a

0–6 × 8 ml^a

0–6 × 8 ml^a

PAXgene for WB RNA transcriptonics

1 × 3 ml

0–1 × 3 ml^a

0–1 × 3 ml^a

0–1 × 3 ml^a

WB in EDTA tube for DNA analysis of B cell and T cell repertoires

1 × 2 ml

0–1 × 2 ml^a

0–1 × 2 ml^a

0–1 × 2 ml^a

Total blood volume (ml)

44.5–60.5 ml

7.5 ml - 60.5 ml

7.5 ml - 60.5 ml

7.5 ml - 60.5 ml