Characteristic | Overall, N = 47,496 | With bacteraemia, n = 11,629 | Without bacteraemia, n = 35,867 | ||||||
---|---|---|---|---|---|---|---|---|---|
CR, n = 2076 | CS, n = 45,420 | P value | CR, n = 201 | CS, n = 11,428 | P value | CR, n = 1875 | CS, n = 33,992 | P value | |
Time between admission and index culture, days | |||||||||
Mean (SD) | 3.6 (10.9) | 2.1 (9.3) | < 0.001 | 5.1 (13.8) | 1.5 (3.9) | < 0.001 | 3.5 (10.5) | 2.3 (10.5) | < 0.001 |
Median (Q1–Q3) | 1 (1.0–2.0) | 1 (1.0–1.0) | < 0.001 | 1 (1.0–1.0) | 1 (1.0–1.0) | < 0.001 | 1 (1.0–2.0) | 1 (1.0–1.0) | < 0.001 |
1 day prior to admission, n (%) | 186 (9.0) | 4285 (9.4) | < 0.001 | 23 (11.4) | 1256 (11.0) | < 0.001 | 163 (8.7) | 3029 (8.9) | < 0.001 |
Same day as admission, n (%) | 1300 (62.6) | 31,927 (70.3) | 139 (69.2) | 9409 (82.3) | 1161 (61.9) | 22,518 (66.2) | |||
Overall LOSa, days | |||||||||
Mean (SD) | 12.5 (23.8) | 9.3 (23.0) | < 0.001 | 18.0 (25.0) | 9.1 (11.8) | < 0.001 | 11.9 (23.6) | 9.4 (25.7) | < 0.001 |
Median (Q1–Q3) | 8 (5.0–12.0) | 6 (4.0–10.0) | < 0.001 | 9 (6.0–16.0) | 7 (5.0–10.0) | < 0.001 | 8 (5.0–12.0) | 6 (4.0–10.0) | < 0.001 |
1–2, n (%) | 57 (2.7) | 1683 (3.7) | < 0.001 | 5 (2.5) | 340 (3.0) | < 0.001 | 52 (2.8) | 1343 (4.0) | < 0.001 |
3–6, n (%) | 729 (35.1) | 21,109 (46.5) | 47 (23.4) | 5256 (46.0) | 682 (36.4) | 15,853 (46.6) | |||
7–10, n (%) | 622 (30.0) | 11,922 (26.2) | 66 (32.8) | 3305 (28.9) | 556 (29.7) | 8617 (25.4) | |||
11–15, n (%) | 303 (14.6) | 5313 (11.7) | 32 (15.9) | 1355 (11.9) | 271 (14.5) | 3958 (11.6) | |||
16+, n (%) | 365 (17.6) | 5393 (11.9) | 51 (25.4) | 1172 (10.3) | 314 (16.7) | 4221 (12.4) | |||
Infection-associated LOSb, days | |||||||||
Mean (SD) | 9.9 (16.3) | 8.2 (15.3) | < 0.001 | 13.9 (16.1) | 8.6 (9.9) | < 0.001 | 9.5 (16.3) | 8.1 (16.7) | < 0.001 |
Median (Q1–Q3) | 7 (5.0–11.0) | 6 (4.0–9.0) | < 0.001 | 9 (6.0–14.0) | 7 (5.0–10.0) | < 0.001 | 7 (5.0–10.0) | 6 (4.0–9.0) | < 0.001 |
1–2, n (%) | 87 (4.2) | 1669 (3.7) | < 0.001 | 6 (3.0) | 314 (2.7) | < 0.001 | 81 (4.3) | 1355 (4.0) | < 0.001 |
3–6, n (%) | 812 (39.1) | 22,924 (50.5) | 45 (22.4) | 5327 (46.6) | 767 (40.9) | 17,597 (51.8) | |||
7–10, n (%) | 639 (30.8) | 12,125 (26.7) | 72 (35.8) | 3435 (30.1) | 567 (30.2) | 8690 (25.6) | |||
11–15, n (%) | 299 (14.4) | 4951 (10.9) | 36 (17.9) | 1349 (11.8) | 263 (14.0) | 3602 (10.6) | |||
16+, n (%) | 239 (11.5) | 3751 (8.3) | 42 (20.9) | 1003 (8.8) | 197 (10.5) | 2748 (8.1) | |||
ICU occurred during index hospitalisation, n (%) | 670 (32.3) | 15,737 (34.7) | 0.026 | 114 (56.7) | 5156 (45.1) | 0.001 | 556 (29.7) | 10,581 (31.1) | 0.179 |
ICU LOS, days | |||||||||
Mean (SD) | 9.0 (21.8) | 5.8 (17.7) | < 0.001 | 14.4 (28.0) | 5.2 (12.0) | 0.001 | 7.9 (20.1) | 6.0 (19.9) | 0.034 |
Median (Q1–Q3) | 3 (1.0–8.0) | 3 (1.0–6.0) | 0.100 | 3 (1.0–10.0) | 3 (1.0–5.0) | 0.172 | 3 (1.0–7.5) | 3 (1.0–7.0) | 0.405 |
Infection-associated ICU stay, n (%) | 520 (25.1) | 12,940 (28.5) | 0.001 | 100 (49.8) | 4713 (41.2) | 0.015 | 420 (22.4) | 8227 (24.2) | 0.076 |
ICU at index culture, n (%) | 413 (19.9) | 9874 (21.7) | 0.046 | 76 (37.8) | 3587 (31.4) | 0.052 | 337 (18.0) | 6287 (18.5) | 0.571 |
Infection-associated ICU LOSc, days | |||||||||
Mean (SD) | 6.5 (14.6) | 4.9 (10.1) | 0.013 | 9.2 (17) | 4.8 (10.2) | 0.011 | 5.9 (13.9) | 5.0 (10.1) | 0.195 |
Median (Q1–Q3) | 3 (1.0–7.0) | 3 (1.0–6.0) | 0.173 | 3 (1.0–8.5) | 3 (1.0–5.0) | 0.373 | 3 (1.0–6.0) | 3 (1.0–6.0) | 0.381 |